Endoplasmic reticulum stress: cell life and death decisions.

By Chunyan Xu, B. Bailly-maitre, John Calvin Reed. Journal of Clinical Investigation, 2005

2,286 citations recorded by the source corpus.

Subfields: Cell Biology, Epidemiology, Surgery

View Paper: https://www.semanticscholar.org/paper/3e4784c31a8496f5ba2836ac283cc983cf42024c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. J. Forbes
2. M. Cooper
3. John Calvin Reed
4. Adi Kimchi
5. Inki Kim
6. W. Xu
7. Guido Kroemer
8. H. Steller

In Epidemiology

1. M. Abdollahi
2. M. J. Saad
3. L. Velloso
4. S. Bordin
5. John Calvin Reed
6. Adi Kimchi
7. M. Maiuri
8. S. Mostafalou

In Surgery

1. J. Forbes
2. M. Cooper
3. John Calvin Reed
4. Yibin Wang

Citations in the corpus

• Self-eating and self-killing: crosstalk between autophagy and apoptosis (2007, background): “Stress that affects the ER is widely known to induce apoptosis through the intrinsic pathwa”
• Mechanisms of diabetic complications. (2013, background): “In diabetes however, it is thought that these ER stress protective pathways are overwhelmed, initiating proapoptotic pathways (302, 654).”
• Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*). (2009, background): “Similarly, in the spondyloarthropathies, misfolding of HLA-B27 appears to trigger the unfolded protein response (UPR) in macrophages and consequently inappropriate cytokine secretion (31–33).”
• Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities (2008, background): “The consequences of triggering the UPR because of ER stress in mammalian cells can be grouped into three types of effector functions: adaptation, alarm and apoptosi”
• Pesticides and human chronic diseases: evidences, mechanisms, and perspectives. (2013, background): “Paraquat has also been noted to impair UPS given by decreased proteasome activity and increased ubiquitinated proteins in DJ-1 deficient mice and dopaminergic neurons (Yang and Tiffany-Castiglioni, 2007; Yang et al., 2007).”
• Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity (2009, background): “Under certain harmful conditions, the ER homeostasis is disrupted, leading to the accumulation of misfolded and unfolded proteins in the ER lumen (Schröder and Kaufman, 2005; Xu et al., 2005).”
• Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. (2010, background): “Finally, ASK-1/JNK is a downstream pathway of ER stress signaling (290), which is also gaining more appreciation as an important aspect of stress signaling in the diseased heart (409, 440).”