WNT and β-catenin signalling: diseases and therapies

By R. Moon, A. D. Kohn, G. Ferrari, A. Kaykas. Nature reviews genetics, 2004

1,659 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/3c66cdafb3edd0635ce88aadc4da6819020ceee6

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Hans Clevers
2. K. Guan
3. R. Nusse
4. David M. Sabatini
5. J. Massagué
6. W. Birchmeier
7. K. Willert
8. K. Jones

Citations in the corpus

• Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum: an entero-bone endocrine axis (2008, background): “mutations in Lrp5 do not cause bone tumors as activation of Wnt signaling does in other organs ( Moon et al., 2004 ).”
• Function and biological roles of the Dickkopf family of Wnt modulators (2006, background): “The Wnt pathway plays an important role in cancer (Polakis, 2000; Moon et al., 2004) and thus it is not surprising that Wnt modulators, including Dkks, are also involved.”
• Emerging roles of Wnts in the adult nervous system (2010, background): “jpg" NDATA ITEM> ]> Wnt proteins are important mediators of cell–cell communication and are involved in diverse cellular processes, including the development of the CN”
• WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis (2009, background): “2006; Klaus and Birchmeier, 2008; Logan and Nusse, 2004; Moon et al., 2004).”
• Wnt signalling and its impact on development and cancer (2008, background): “Moreover, uncontrolled Wnt–β-catenin signalling that is associated with elevated β-catenin levels is also linked to aggressive fibromatosis and pulmonary fibrosi”
• Wnt signaling: is the party in the nucleus? (2006, background): “…roles of Wnt signaling in development, organogenesis, and cancer, we refer the reader to several excellent recent reviews (Bienz and Hamada 2004; Moon et al. 2004; Nelson and Nusse 2004; Bienz 2005; Gregorieff and Clevers 2005; Kohn and Moon 2005; Radtke and Clevers 2005; Reya and Clevers 2005).”
• Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. (2006, background): “The Wnt family of secreted signal proteins plays a key role in numerous aspects of embryogenesis, as well as in carcinogenesis (Logan and Nusse, 2004; Moon et al., 2004; Reya and Clevers, 2005).”