To be or not to be? How selective autophagy and cell death govern cell fate.

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Small molecule inhibition of the autophagy kinase ULK1 and identification of ULK1 substrates (2015, background): “Defects in autophagy pathways have been associated with a number of human pathologies, including infectious diseases, neurodegenerative disorders, and cancer (Green and Levine, 2014).”
Recent insights into the function of autophagy in cancer (2016, background): “…realization that the regulated expression of specialized cargo receptors allows the cell to promote one type of selective autophagy over another (Green and Levine 2014), it is also timely to consider how one can exploit inactivation of such selective adaptor proteins to parse out the different…”
Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor (2016, positive): “Mitophagy is crucial for protecting cells against deleterious effects of damaged mitochondria and for fundamental processes in eukaryotic development, including the uniparental inheritance of mtDNA (Green and Levine, 2014; Redmann et al., 2014).”
Molecular definitions of autophagy and related processes (2017, neutral): “…nutritional, metabolic, chemical, physical, and hormonal cues can alter (increase or decrease) the ability of microautophagy, CMA, and macroautophagy to degrade autophagy substrates (Galluzzi et al , 2014; Green & Levine, 2014; Kaur & Debnath, 2015; Mukherjee et al , 2016; Tasset & Cuervo, 2016).”