Maternal Care and Hippocampal Plasticity: Evidence for Experience-Dependent Structural Plasticity, Altered Synaptic Functioning, and Differential Responsiveness to Glucocorticoids and Stress

By D. Champagne, R. Bagot, F. V. van Hasselt, Ger J. A. Ramakers, Michael Joseph Meaney, E. D. de Kloet, Marian Joëls, H. Krugers. Journal of Neuroscience, 2008

694 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cognitive Neuroscience, Social Psychology

View Paper: https://www.semanticscholar.org/paper/4a822dd209ae400a6de78921d6718fcf6ff2d636

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Citations in the corpus

Epigenetics for behavioral ecologists (2013, background): “2004) and an inherited propensity for learning (Champagne et al. 2008) might be mediated by environmentally induced epigenetic factors, and can thus be targets of selection.”
Epigenetics and the biological definition of gene x environment interactions. (2010, background): “…the benign conditions described earlier but in tests on contextual fear conditioning, the performance of the offspring of the low-LG mothers is significantly improved (i.e., increased learning of the context–shock contingency) over that of high-LG dams (Bagot et al., 2009; Champagne et al., 2008).”
Does Early-Life Exposure to Stress Shape or Impair Cognition? (2013, neutral): “Other work shows that rat pups of low-caring mothers better memorize fearful contexts (Bagot et al., 2009; Champagne et al., 2008) and more readily learn to associate neutral stimuli (a tone) with fearsome stimuli (e.”
Intergenerational Trauma: Convergence of Multiple Processes among First Nations peoples in Canada (2009, neutral): “Moreover, to this list one can add that early positive life experiences augment resilience (Champagne et al., 2008).”
The neuro-symphony of stress (2009, background): “The slow, gene-mediated consequences of GR activation depend on the life history; for example, adverse early-life experiences or chronic stress in adulthood influence the number and the functioning of GRs in the hippocampu”
Paradise Lost: The Neurobiological and Clinical Consequences of Child Abuse and Neglect. (2016, background): “…low maternal licking and grooming in rats revealed shorter dendritic branch length and lower spine density in CA1 cells of low licking and grooming animals, as well as significantly impaired hippocampal long-term potentiation (LTP) and reduced GC and MR receptor density (Champagne et al., 2008).”
The Adaptive Calibration Model of stress responsivity (2010, positive): “spine density in hippocampal neurons), they actually enhance learning and memory processes under stressful conditions (Bagot et al., 2009; Champagne et al., 2008).”
Early maternal deprivation affects dentate gyrus structure and emotional learning in adult female rats (2010, neutral): “Functional consequences of maternal deprivation Chronic early life stress and low levels of maternal care are known to impair LTP in area CA3 (Brunson et al. 2005), CA1 (Champagne et al. 2008) and in the DG (Bagot et al. 2009).”
Natural variations in maternal and paternal care are associated with systematic changes in oxytocin following parent-infant contact. (2010, background): “An important feature of the oxytocinergic system that underlies the formation of affiliative bonds is its modification by early social experience (Meaney, 2001; Champagne et al., 2008).”
Differential susceptibility to the environment: An evolutionary–neurodevelopmental theory (2011, background): “stressful conditions (Champagne et al., 2008).”
Child Development in the Context of Adversity (2012, background): “…specifically, or in low-resource, unpredictable caregiving environments more generally, altered HPA axis responsivity, biased attributional style, and hypervigilance to environmental cues allow for more rapid learning and response to conditions of threat (Champagne et al., 2008; Pollak, 2008).”