Pancreatic cancer.
By C. Chrystoja, Eleftherios P. Diamandis, R. Brand, F. Rückert, R. Haun, R. Molina. Clinical Chemistry, 2013
8,552 citations recorded by the source corpus.
Subfields: Oncology
View Paper: https://www.semanticscholar.org/paper/3aa15b2978c4aeecb247c3d99ba7d5264e8549dd
How researchers see this paper
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In Oncology
- D. Tuveson
- N. Desai
- V. Bronte
- D. Bar-Sagi
- Y. Pylayeva-Gupta
- S. Prasad
- Bharat B. Aggarwal
- Prashanth Rawla
Citations in the corpus
- Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial. (2011, background): “is a lethal disease with approximately 6 months of median survival.(1,2) Gemcitabine is the only”
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Diminished Survival (2014, neutral): “Pancreatic ductal adenocarcinoma (PDAC) is a near uniformly lethal disease with a dismal median survival of 4 to 6 months (Hidalgo, 2010; Korc, 2007).”
- Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. (2015, neutral): “One of the most lethal forms of cancer is pancreatic ductal adenocarcinoma (PDAC) (1).”
- The dynamic nature of autophagy in cancer. (2011, background): “Autophagy was first discovered >40 years ago in mammalian cells as a process of self-digestion and was initially thought to be a nonspecific bulk degradation process (De Duve and Wattiaux 1966; Klionsky 2008; Yang and Klionsky 2010a).”
- Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors (2019, methodology): “Several germ-line mutations have been identified to be involved in hereditary forms of pancreatic cancer, such as BRCA1, BRCA2, PALB2, ATM, CDKN2A, APC, MLH1, MSH2, MSH6, PMS2, PRSS1 and STK11 [138, 143].”
- Variations of oral microbiota are associated with pancreatic diseases including pancreatic cancer (2011, background): “5 Around 15%e20% of patients have surgically resectable disease at the time of presentation, but only around 20% of these survive to 5 years.(3) Cigarette smoking is considered to be the only established modifiable risk factor for cancer of the pancreas, although some data also suggest an associatio”
- Inflammatory responses and inflammation-associated diseases in organs (2015, background): “Pancreatic cancer results from dysregulation of oncogenes and tumor suppressor genes, as well as growth factors and their receptors, including epidermal growth factors, vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and many cytokines, such as TGF-β, IL-1, IL-6, TNF-α, an”