Extracellular DNA required for bacterial biofilm formation.

By C. Whitchurch, T. Tolker-Nielsen, P. Ragas, John S. Mattick. Science, 2002

2,157 citations recorded by the source corpus.

Subfields: Ecology, Microbiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/391a368bcee252071483f0497f10b255ccc3b911

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Ecology

1. P. Nannipieri
2. R. Vasudevan
3. P. Watnick
4. E. Karatan
5. D. Wozniak
6. T. Bjarnsholt
7. M. Parsek
8. M. Ceccherini

In Microbiology

1. M. Otto
2. A. Horswill
3. Aleeza J. Roth
4. Matthew J. Thoendel
5. Blaise R. Boles
6. Adam Kulp
7. M. Kuehn
8. A. Decho

In Molecular Biology

1. T. Bjarnsholt
2. M. Otto
3. P. Watnick
4. E. Karatan
5. M. Givskov
6. R. Vasudevan
7. Niels Høiby
8. A. Horswill

Citations in the corpus

• Extracellular DNA Chelates Cations and Induces Antibiotic Resistance in Pseudomonas aeruginosa Biofilms (2008, background): “Consistent with previous reports that DNA is a component of biofilms [50,51], we observed DNA in 24 h old peg-adhered biofilms (Fig 5A and 5B).”
• Thematic Issue on Horizontal Gene Transfer Review Release and persistence of extracellular DNA in the environment (2007, neutral): “Recent studies suggest extracellular DNA is an important component of bacterial biofilms (Steinberger and Holden, 2005; Whitchurch et al., 2002).”
• Staphylococcal biofilms (2018, background): “The biofilm matrix component eDNA is subject to degradation by nucleases, which originally has been shown using human DNase I (70), which is abundant in human serum.”
• Biosynthesis of Extracellular Polymeric Substances (EPS) and Its Role in Microbial Biofilm Formation (2007, background): “Extracellular Dna has recently been described as one of a major structural components of the Pseudomonas aeruginosa and Streptococcus mutans biofilm matrix [5, 57].”
• Biofilm Formation in Food Processing Environments is Still Poorly Understood and Controlled (2014, background): “Some microorganisms can form biofilms that harbour other microorganisms less prone to biofilm formation, increasing the probability of the many strains survival (Whitchurch et al. 2002; Djordjevic et al. 2002).”
• Biofilms: the matrix revisited. (2005, background): “For example, a recent report indicates that extracellular DNA plays an important role in the establishment of biofilm structure [ 13 ].”
• Exopolysaccharides of the Biofilm Matrix: A Complex Biophysical World (2012, background): “The elastic relaxation time of about 30 minutes lies within the range previously determined for various biofilms [4].”
• Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms (2003, background): “Chemical analyses of P. aeruginosa SSA biofilms formed in flow cells suggest that the matrix that encases the cells in such biofilms is composed of water, exopolysaccharide, DNA, RNA, proteins and ions (Sutherland, 2001; Whitchurch et al., 2002).”