Oxygen in acute and chronic wound healing

By S. Schreml, R. Szeimies, Lukas Prantl, S. Karrer, M. Landthaler, P. Babilas. British Journal of Dermatology, 2010

738 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Rehabilitation, Surgery

View Paper: https://www.semanticscholar.org/paper/37c5cef5587948c858b1a8714952e4684c16976f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

1. R. Frykberg
2. Jaminelli Banks

In Rehabilitation

1. Rui Yu
2. R. Frykberg
3. M. Xue
4. Jaminelli Banks
5. Baolin Guo
6. C. Jackson

In Surgery

1. R. Frykberg
2. Jaminelli Banks

Citations in the corpus

• Inflammation in Chronic Wounds (2016, background): “During reperfusion, an over-abundance of leukocytes including neutrophils migrate into the wound tissue; there, they produce inflammatory cytokines and ROS, compounded by ROS from partial tissue reoxygenation [52].”
• Wound dressings – a review (2015, background): “It heals at a predictable and expected time frame usually within 8-12 weeks depending on the size, depth and the extent of damage in the epidermis and dermis layer of the skin [3, 4].”
• Challenges in the Treatment of Chronic Wounds (2015, background): “This sequence of events leads to an enhanced stimulation of proteases and inflammatory cytokines.(17) It has been suggested in an animal model that application of strong antioxidants reduces ROS to normal levels, which results in the reverse of the chronicity of wounds and improves healing.”
• Conductive Biomaterials as Bioactive Wound Dressing for Wound Healing and Skin Tissue Engineering (2021, background): “1007/s40820-021-00751-y © The authors including physiological signals [168], pH [193, 249, 251, 252, 254], oxygen [19], temperature [239], moisture [256], glucose [193, 250], and uric acid [257].”
• Oxidative stress in angiogenesis and vascular disease. (2014, background): “VEGF signaling is ultimately required for normal vascular development and homeostasis, but it is also actively engaged in tumor progression by promoting growth of tumor vasculature.41 This signaling pathway often seems to be affected by ROS.”