Oxidative stress in angiogenesis and vascular disease.

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Endothelial Dysfunction and Hypertension. (2016, background): “VEGF also contributes to the inflammatory response through stimulation of the release of adhesion molecules, MMPs and NO, via the transcription factor activator protein-1 (AP-1) (Kim and Byzova 2014; Jaipersad et al. 2014).”
Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases. (2018, background): “In particular, the NOX2 and NOX4 isoforms induce proliferation and survival of endothelial cells via ROS-mediated p38 MAPK and Akt activation [42].”