Modulation of Protein Kinase Activity and Gene Expression by Reactive Oxygen Species and Their Role in Vascular Physiology and Pathophysiology

By K. Griendling, D. Sorescu, B. Lassègue, M. Ushio-Fukai. Arteriosclerosis, Thrombosis and Vascular Biology, 2000

999 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/372cd3678670dff41f0b49eb87b8168473edfeb1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Alexander H Sprague
2. R. Khalil
3. E. Schiffrin
4. Rhian M. Touyz
5. T. Paravicini
6. S. Dikalov
7. Rui‐Ming Liu
8. L. Desai

In Molecular Biology

1. Alexander H Sprague
2. R. Khalil
3. E. Schiffrin
4. Rhian M. Touyz
5. S. Dikalov

In Physiology

1. Rhian M. Touyz
2. E. Schiffrin
3. R. Khalil
4. T. Paravicini
5. S. Dikalov
6. Rui‐Ming Liu
7. L. Desai

Citations in the corpus

• Crosstalk between mitochondria and NADPH oxidases (2011, background): “The effect of mitochondrial ROS on NADPH oxidase activity is quite probably mediated by c-Src [5], which can be stimulated by H2O2 [4].”
• Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities (2011, neutral): “B. Redox-dependent cell signaling, growth, and survival ROS may play an essential role in receptor activation and downstream signaling (64, 122, 141, 145).”
• Inflammatory Cytokines in Vascular Dysfunction and Vascular Disease (2009, background): “In HTN, mechanical stress on arterial wall and proinflammatory humoral stimuli such as AngII and ET-1 induce oxidative stress, which could cause vascular inflammation [26].”
• Oxidative Stress and the Central Nervous System (2017, neutral): “The antioxidant enzyme system includes superoxide dismutase (SOD), glyoxalase, glutathione reductase, glutathione peroxidase, and catalase (CAT) (Griendling et al., 2000).”
• NADPH Oxidases in Cardiovascular Health and Disease (2006, neutral): “In the cardiovascular system, these include vascular smooth muscle cells (VSMC) (118, 336), endothelial cells EC) (24, 25, 111, 166), adventitial and cardiac fibroblasts 44, 263), and cardiomyocytes (29, 203, 355, 362).”
• Redox signaling in hypertension. (2006, background): “[4] Griendling KK, Sorescu D, Lassegue B, Ushio-Fukai M.”
• Reactive oxygen species in vascular biology: implications in hypertension (2004, positive): “The pathogenic outcome of oxidative stress is oxidative damage (Griendling et al. 2000a; Schafer and Buettner 2001; Zalba et al. 2001a), a major cause of vascular injury in hypertension.”
• The effects of oxidative stress on female reproduction: a review (2012, neutral): “altered gene expression [48,213].”