Redox signaling in hypertension.

By T. Paravicini, Rhian M. Touyz. Cardiovascular Research, 2006

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Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? (2007, background): “by direct Cys oxidation or indirectly by concomitant inhibition of phosphatases; and it leads to the activation or inactivation of various transcription factors (such as HIF1α and nuclear factor (NF)-κB, respectivel”
Antimicrobial strategies centered around reactive oxygen species--bactericidal antibiotics, photodynamic therapy, and beyond. (2013, background): “…in macromolecular damage and is implicated in various diseases including and not limited to atherosclerosis (Paravicini & Touyz, 2006), diabetes (Paravicini & Touyz, 2006), carcinogenesis, and tumor metastasis through gene activation (Ishikawa et al., 2008; Trachootham et al., 2009),…”
Oxidative Stress in Cardiovascular Diseases: Still a Therapeutic Target? (2019, background): “Cumulated evidence indicates that oxidative stress could be a contributing factor in the pathogenesis of hypertension [79,80].”
Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies. (2016, background): “VSMCs also correlated with the activation of MAPK through ERK activation [121] and cyclin D1 up regulation [122].”