Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin.

By B. Feagan, G. Greenberg, G. Wild, R. Fedorak, P. Paré, J. McDonald, R. Dubé, A. Cohen, A. Steinhart, S. Landau and 3 more. New England Journal of Medicine, 2005

701 citations recorded by the source corpus.

Subfields: Genetics, Immunology and Allergy, Neurology

View Paper: https://www.semanticscholar.org/paper/36d7bc4b13563dd666a5f851a9ccf277716814d4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. R. Sartor
2. J. Turner

In Immunology and Allergy

1. R. Alon
2. A. Luster

Citations in the corpus

• Neutrophils and immunity: challenges and opportunities (2006, background): “Antibodies directed against adhesion molecules expressed by lymphocytes have shown benefit in some setting”
• Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis (2006, methodology): “while a humanized anti-integrin-α 4 β 7 antibody has been used to treat active ulcerative colitis”
• Immune cell migration in inflammation: present and future therapeutic targets (2005, background): “In fact, a 'humanized' monoclonal antibody that blocks the α 4 β 7 heterodimer but not the individual components is effective for the treatment of ulcerative coliti”