Neuronal replacement from endogenous precursors in the adult brain after stroke

By A. Arvidsson, T. Collin, D. Kirik, Z. Kokaia, O. Lindvall. 2002

2,915 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology

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Citations in the corpus

Adult neurogenesis in brain repair: cellular plasticity vs. cellular replacement (2014, background): “Similarly, migration of newly generated neurons to the site of damage has been reported following brain ischemia (Arvidsson et al., 2002; Thored et al., 2007).”
Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “Stroke induces cell proliferation and migration of newborn neurons to infarct sites, the vast majority of which fail to survive over the long term, presumably due to a lack of functional connections and trophic support (Arvidsson et al., 2002).”
Neurogenesis in the striatum of the adult human brain. (2014, neutral): “It is well documented that substantial numbers of striatal neurons are generated from the subventricular zone in both rodents and monkeys in response to stroke (Arvidsson et al., 2002; Hou et al., 2008; Tonchev et al., 2005; Tonchev et al., 2003; Wei et al., 2011).”
A Neurovascular Niche for Neurogenesis after Stroke (2006, background): “…express phenotypic markers of mature neurons, including neuronalspecific nuclear protein (NeuN), and region-specific mature neuronal markers, such as calbindin and dopamine and cAMPregulated phosphoprotein-32 (Arvidsson et al., 2002; Parent et al., 2002), and form synapses (Yamashita et al., 2006).”
Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells (2006, background): “Additional important evidence can be obtained by analysis of progressive differentiation in the sense of progression through different markers of increasing neuronal (or other cell type) differentiation over time after the cell division (Magavi et al. 2000; Arvidsson et al. 2002; Magavi & Macklis 20”
Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. (2004, background): “Expression of doublecortin (DCX), a marker of immature, or early, neurons (20), was principally restricted to NPCs close to the SVZ (Figure 4D).”
Stem cell therapy for human neurodegenerative disorders–how to make it work (2004, background): “Stroke leads to increased generation of neurons from NSCs in the subventricular zone (SVZ”
Neurogenesis in the adult brain: new strategies for central nervous system diseases. (2004, background): “In the study of Arvidsson and colleagues (124), only 20% of the new striatal neurons that were initially generated survived longer than two weeks, and only half of these cells expressed markers that were consistent with a mature, striatal neuronal phenotype.”
Adult generation of glutamatergic olfactory bulb interneurons (2009, background): “Indeed, many new neuroblasts migrate into the striatum and generate GABAergic neurons after strok”