Time-dependent reorganization of brain circuitry underlying long-term memory storage

By B. Bontempi, C. Laurent-Demir, C. Destrade, R. Jaffard. 1999

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Y. Dudai
2. Xu Han
3. Zhiyuan Liu
4. Maosong Sun
5. Tianyu Gao
6. L. R. Squire
7. German Ignacio Parisi
8. Karim Nader

Citations in the corpus

• Continual Lifelong Learning with Neural Networks: A Review (2018, background): “, long-term memories; Bontempi et al. (1999)). Kitamura et al. (2017) showed that, when the brain learns something new, the hippocampus and PFC are both initially encoded with the corresponding memory; however, the hippocampus is primarily responsible for the recent recall of new information.”
• FearNet: Brain-Inspired Model for Incremental Learning (2017, background): “In contrast, mPFC is responsible for the recall of remote (long-term) memories (Bontempi et al., 1999).”
• Replay in Deep Learning: Current Approaches and Missing Biological Elements (2021, neutral): “While the hippocampus allows for the quick assimilation of new information, medial prefrontal cortex is used for long-term storage of memories and generalization (Bontempi et al., 1999).”
• Continual Relation Learning via Episodic Memory Activation and Reconsolidation (2020, methodology): “In fact, these memory-based methods are similar to long-term memory model of mammalian memory in neuroscience (McClelland et al., 1995; Bontempi et al., 1999).”
• New circuits for old memories: the role of the neocortex in consolidation. (2004, background): “Bontempi et al. (1999) were also the first to point to age, or retrieval of these memories.”
• The hippocampus and related neocortical structures in memory transformation. (2018, background): “In rodents, reliance on the mPFC emerges over time [73,74,153,154] but there is evidence that early communication be-tween the hippocampus and mPFC is required for the formation of the remote mPFC memory network [142].”
• The organization of recent and remote memories (2005, unknown): “Recent studies have used imaging approaches to track changes in networks over periods of weeks in healthy animal”
• The neurobiology of consolidations, or, how stable is the engram? (2004, background): “…postacquisition temporally graded activity in mediotemporal structures in the human brain (Haist et al. 2001), and in the hippocampal formation in mice (Bontempi et al. 1999), which suggests that time-dependent reorganization of brain circuitry is involved in the formation of long-term memory.”
• Cellular and systems reconsolidation in the hippocampus. (2002, background): “Reconsolidation did not show any temporally graded gradient across the time pendent on other cortical areas (Bontempi et al., 1999; Frankland et al., 2001 ).”
• Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus. (2007, unknown): “Recent studies have started to address this issue of memory persistence, focusing mainly on the neocortex as the region of permanent memory storage (Bontempi et al., 1999; Burwell et al., 2004; Frankland et al., 2004; Maviel et al., 2004).”
• The medial temporal lobe. (2004, background): “Metabolic activity decreased in the hippocampus from 5 to 25 days after learning but increased in frontal, anterior cingulate, and temporal neocortex (Bontempi et al. 1999).”