Cellular and systems reconsolidation in the hippocampus.

By J. Debiec, Joseph E LeDoux, Karim Nader. Neuron, 2002

758 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Social Psychology

View Paper: https://www.semanticscholar.org/paper/bf9f97e7eff80964ac07a51e2479cacfb911f10c

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Citations in the corpus

Contextual Fear Memories Formed in the Absence of the Dorsal Hippocampus Decay Across Time (2012, background): “Importantly, systems consolidation is distinct from cellular consolidation (Debiec et al., 2002), which provides a mechanism for the transition from active short-term memory to passive long-term memory in a process that occurs for several hours after the acquisition or retrieval of information…”
Reactivation of neural ensembles during the retrieval of recent and remote memory. (2013, neutral): “Previous work indicates that context fear gradually becomes independent of the hippocampus after learning [29–32].”
Activation of Hippocampal Nuclear Factor-κB by Retrieval Is Required for Memory Reconsolidation (2007, neutral): “On the one hand, data support hippocampal involvement in both consolidation and reconsolidation (Debiec et al., 2002; Rossato et al., 2006), and, in contrast, data support that hippocampus is involved in consolidation but not in reconsolidation (Taubenfeld et al., 2001; Tronel et al., 2005).”
The restless engram: consolidations never end. (2012, background): “They were demonstrated mostly in synaptic consolidation but shown to occur also in systems consolidation (Debiec et al. 2002, Winocur et al. 2009).”
A computational theory of hippocampal function, and empirical tests of the theory. (2006, background): “This raises the issue of the possible gradient of retrograde amnesia following hippocampal damage, and of whether information originally hippocampus-dependent for acquisition gradually becomes ‘‘consolidated’’ in the neocortex and thereby becomes hippocampus-independent over time (Debiec et al., 200”
New circuits for old memories: the role of the neocortex in consolidation. (2004, background): “Patients with the brain (McGaugh, 2000; Debiec et al., 2002; Dudai, MTL damage have great difficulty forming new long2004; Dash et al., 2004). term memories (Scoville and Milner, 1957; Penfield and In humans, research on consolidation has focused on Milner, 1958; Corkin, 1984).”
Mechanisms of memory stabilization: are consolidation and reconsolidation similar or distinct processes? (2005, methodology): “those of Nader et al. [7] and Debiec et al. [ 11 ]), brain regions required or activated in consolidation are not engaged in reconsolidation.”
Sleep, memory, and plasticity. (2006, background): “Following reactivation and blockade of reconsolidation, previously learned behaviors are still intact 2 hours (Suzuki et al. 2004) and 4 hours (Debiec et al. 2002, Duvarci & Nader 2004, Nader et al. 2000) later, with no sign that degradation has begun.”
A single standard for memory: the case for reconsolidation (2009, background): “However, there are also many examples of studies in which these boundary conditions were not detected (for extinction [29, 119], old memories [22, 58], or strength of training [22, 58]).”