Regulated transport of the glucose transporter GLUT4

By Nia J Bryant, R. Govers, D. James. Nature reviews. Molecular cell biology, 2002

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Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins (2003, background): “Insulin acts by stimulating the translocation of specific GLUT4-containing vesicles from intracellular stores to the plasma membrane resulting in an immediate 10–20-fold increase in glucose transport (Shepherd & Kahn, 1999; Bryant et al. 2002).”
Store-operated calcium channels. (2005, neutral): “Such a mechanism would be analogous to insertion of other channels and transporters following cell-surface stimulation including aquaporin2 water channels in collecting tubules of the kidney by vasopressin (47), the glucose transporter GLUT4 in adipocytes and skeletal muscle by insulin (49), and the”
SNAREs and traffic. (2005, background): “VAMP8 was recently shown to be the premier v-SNARE of zymogen granules in pancreatic acinar cells and it mediates regulated fusion with the apical surface, interacting with t-SNARE assembled from Syn4 and SNAP-23 [62].”
Metabolic Syndrome and Insulin Resistance: Underlying Causes and Modification by Exercise Training (2013, neutral): “The mechanisms and cellular machinery involved in GLUT4 packaging and trafficking are reviewed in detail elsewhere (89, 167, 332, 348, 383, 402, 443, 444, 501, 680).”