Direct selection of human genomic loci by microarray hybridization

By Thomas Albert, Michael Molla, D. Muzny, L. Nazareth, D. Wheeler, Xingzhi Song, Todd A. Richmond, C. Middle, M. Rodesch, C. Packard and 2 more. Nature Methods, 2007

698 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/33998238875aee03c927d6d7412dedc26a28cd6f

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In Molecular Biology

Citations in the corpus

Advances in understanding cancer genomes through second-generation sequencing (2010, neutral): “Nature 463, 899–905 (2010).”
DNA sequencing at 40: past, present and future (2017, positive): “In this period, whole-genome sequencing (WGS) remained too expensive for most groups to scale, motivating the development of targeted capture methods 93–96 and then whole-exome sequencing (WES), that is, selective sequencing of the 1–2% of the genome that is encodes proteins 97 .”
Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture (2012, background): “…application of next-generation sequencing technology is to enrich sample libraries for a targeted subsection of the genome (like all the exons) (Albert et al. 2007; Hodges et al. 2007; Gnirke et al. 2009), and then to sequence this enriched pool of DNA, but such experiments are expensive…”
Targeted Capture and Massively Parallel Sequencing of Twelve Human Exomes (2009, positive): “A comparison of our data to past reports on exonic 18 or exomic 8 array-based capture revealed roughly equivalent capture specificity, but greater completeness in terms of coverage and variant calling (Supplementary Table 2).”
High-Throughput Genomic Data in Systematics and Phylogenetics (2013, methodology): “Hybrid enrichment was originally performed in solid phase using microarrays (e.g., Albert et al. 2007) but is now more commonly performed in solution phase using biotinylated RNA probes or “baits” (Gnirke et al. 2009).”
Sequencing technologies — the next generation (2010, neutral): “oligonucleotide microarrays have been designed to provide complementary sequences for solid-phase hybridization to enrich for exon”
Anchored hybrid enrichment for massively high-throughput phylogenomics. (2012, background): “sequence capture) uses oligonucleotides as baits that hybridize to genomic fragments containing the target sequence and allows target loci to be separated from nontarget regions of the genome (Albert et al. 2007; Gnirke et al. 2009).”
A large genome centre’s improvements to the Illumina sequencing system (2008, background): “Also, because the size distribution of DNA fragmented by AFA is narrow, for some applications, such as array enrichment of targeted loc”
Target-enrichment strategies for next-generation sequencing (2010, positive): “Roche NimbleGen and their collaborators were the first to adapt the technology to be compatible with next-generation sequencing 15,16,39 .”
SNP discovery and allele frequency estimation by deep sequencing of reduced representation libraries (2008, background): “Recently, RRLs produced by direct selection of target fragments from microarray hybridization has been describe”
Genetic diagnosis by whole exome capture and massively parallel DNA sequencing (2009, methodology): “Methods of enriching targeted genomic segments by hybridization have been used for 30 years (10), and have recently been extended to the whole exome scale (11), although their utility has been limited by the large amounts of genomic DNA required and by coupling to sequence platforms of modest throug”