The biology of chromatin remodeling complexes.

By Cedric R Clapier, B. Cairns. Annual Review of Biochemistry, 2009

2,340 citations recorded by the source corpus.

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Citations in the corpus

Epigenetic modifications and human disease (2010, background): “However, NURF, another complex of this family, is capable of activating RNA polymerase II thus participating in transcriptional activatio”
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing (2020, background): “As none of the remodelers with spacing activity can disassemble nucleosomes (Clapier and Cairns, 2009) and thereby affect nucleosome density, their rulers can only set their respective linker lengths if these are shorter than or equal to the density-determined linker length at equidistant…”
Mechanisms and Functions of ATP-Dependent Chromatin-Remodeling Enzymes (2013, critical): “This is, in effect, opposite to previously proposed models involving extra DNA being drawn into the nucleosome in the form of loops before it could exit from the other side (Figure 2) (Clapier and Cairns, 2009).”
Enhancer function: new insights into the regulation of tissue-specific gene expression (2011, neutral): “This task is also carried out by enhancer-bound transcription factors that can recruit histone modifying enzymes or ATP-dependent chromatin remodelling complexes to alter chromatin structure and increase the accessibility of the DNA to other protein”
Cancer Genetics and Epigenetics: Two Sides of the Same Coin? (2012, background): “Chromatin Remodeling Complexes Nucleosome occupancy is a key mechanism for gene expression, and it has been known for some time that chromatin remodelers are responsible for regulating this process (Clapier and Cairns, 2009; Segal and Widom, 2009; Valouev et al., 2011).”
Transcriptional Regulation and its Misregulation in Disease (2013, positive): “Gene activation is accompanied by recruitment of ATP-dependent chromatin remodeling complexes of the SWI/SNF family, which mobilize nucleosomes to facilitate access of the transcription apparatus and its regulators to DNA (Clapier and Cairns, 2009; Hargreaves and Crabtree, 2011).”
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals. (2015, background): “Histone modifications also help regulate replication, recombination, and higher-order organization of the chromosomes (88).”
Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective (2012, background): “In order to get access to the relevant segments of DNA for various processes in DNA metabolism, eukaryotic cells use ATP-dependent chromatin-remodeling enzymes (CRE) which alter the structure and/or position of the nucleosomes [182, 1960, 1961, 1962, 1963, 1964, 1965, 1966, 1967].”
Learning the human chromatin network from all ENCODE ChIP-seq data (2015, background): “Chromatin factors — such as transcription factors, histones, and other DNA-associated proteins — interact with each other to regulate gene expression [10], the physical structure of the genome [7], cell di ↵ erentiation [4], and other cellular processes.”