Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor.

By Takayuki Tohge, Yasutaka Nishiyama, M. Hirai, Mitsuru Yano, J. Nakajima, M. Awazuhara, Eri Inoue, Hideki Takahashi, D. Goodenowe, M. Kitayama and 3 more. The Plant Journal, 2005

958 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/31f6b3d274153572462bf8b9780f0d6dd7173fbb

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Citations in the corpus

Glycosyltransferases: key players involved in the modification of plant secondary metabolites (2009, background): “In the case of flavonols, Jones et al. (2003) identified two GTs (UGT73C6 and UGT78D1) and Tohge et al. (2005) identified three GTs (UGT79B1, UGT75C1 and UGT78D2) involved in the biosynthesis of flavonol glycosides in Arabidopsis.”
The flavonoid biosynthetic pathway in Arabidopsis: structural and genetic diversity. (2013, positive): “Intriguingly, since the major anthocyanin A11 was isolated in Col-7 [19], it has been found in several other accessions including Col-0 [20,26] and C24, Can, Co, Cvi, Ler, Rsch and Te [45] as a major anthocyanin.”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “Briefly, anthocyanins and glycosylated kaempferol flavonols are mostly found in leaves (Tohge et al., 2005; Yonekura-Sakakibara et al., 2008), whereas seeds contain epicatechin, PAs, and larger amounts of glycosylated quercetin flavonols (Kerhoas et al.”
Red colouration in apple fruit is due to the activity of the MYB transcription factor, MdMYB10 (2007, background): “Arabidopsis DFR (TT3, AT5g42800) was isolated from genomic Arabidopsis DNA.”
The cinnamate/monolignol pathway (2010, background): “Although both accumulation of PAL transcripts and PAL activity in pap1-D were increased compared with the wild-type (Borevitz et al. 2000), the genes involved in the monolignol biosynthetic pathway were not upregulated by AtPAP1, except 4CL (Tohge et al. 2005).”
Approaches for extracting practical information from gene co-expression networks in plant biology. (2007, background): “Combined gene–metabolite co-expression analysis using a plant overexpressing PAP1 transcription factor also identified novel glucosyltransferase genes involved in anthocyanin biosynthesis (Tohge et al. 2005).”
Acyltransferases in plants: a good time to be BAHD. (2006, background): “[52] identified two upregulated BAHD family members, At1g03940 and At3g29590, that share high sequence identity with known anthocyanin acyltransferases.”
Light-Induced Expression of a MYB Gene Regulates Anthocyanin Biosynthesis in Red Apples1 (2006, background): “For example, overexpression of the MYBs LeANT1 and AtPAP1 in tomato and Arabidopsis, respectively, induces genes involved in flavonoid modification and transport into vacuoles (Mathews et al., 2003; Tohge et al., 2005).”
Sucrose-Specific Induction of Anthocyanin Biosynthesis in Arabidopsis Requires the MYB75/PAP1 Gene1 (2005, background): “MYB75/PAP1 is a positive regulator of anthocyanin synthesis (Borevitz et al., 2000), which induced the expression of genes involved in anthocyanin synthesis (Tohge et al., 2005).”
The Phenylpropanoid Pathway in Arabidopsis (2011, background): “Wild-type Arabidopsis plants and the sng1-1 mutant accumulate a number of sinapoylated anthocyanins (Bloor and Abrahams, 2002; Tohge et al., 2005; Fraser et al., 2007), but the sng1-5 and sng1-6 mutants do not.”
The Jasmonate-ZIM-Domain Proteins Interact with the WD-Repeat/bHLH/MYB Complexes to Regulate Jasmonate-Mediated Anthocyanin Accumulation and Trichome Initiation in Arabidopsis thaliana[C][W] (2011, background): “…thaliana, the WD-repeat protein Transparent Testa Glabra1 (TTG1) (Walker et al., 1999) recruits basic-helixloop-helix (bHLH) transcription factors (Toledo-Ortiz et al., 2003), such as Glabra3 (GL3) (Payne et al., 2000), Transparent Testa8 (TT8) (Nesi et al., 2000;Baudryet al., 2006), or…”