Impact of the gyral geometry on the electric field induced by transcranial magnetic stimulation

By Axel Thielscher, Alexander Opitz, Mirko Windhoff. NeuroImage, 2011

430 citations recorded by the source corpus.

Subfields: Neurology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/31a351502bbb69fbfa75b83f8f1ae29a2888639b

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Citations in the corpus

Field modeling for transcranial magnetic stimulation: A useful tool to understand the physiological effects of TMS? (2015, methodology): “Starting with no or simple geometries such as infinite half planes or spheres [1, 2], increasingly accurate head models became available within the last few years [3].”
How the brain tissue shapes the electric field induced by transcranial magnetic stimulation (2011, methodology): “…GM structures and U-fibres might significantly contribute to the overall neural activity induced by TMS. Extending our previous hypothesis (Thielscher et al., 2011), we therefore suggest that the stimulation of sulcal regions like the motor cortex at the optimal coil orientation might…”
Electric field depth–focality tradeoff in transcranial magnetic stimulation: simulation comparison of 50 coil designs (2012, neutral): “to that of free space since the quasistatic approximation is applicable to TMS [121] and since permittivity will not affect the”
Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee (2015, methodology): “Detailed modeling studies of the electric field distributions induced by TMS in realistic models of the brain are still being undertaken (Thielscher et al., 2011; Laakso et al., 2014a, 2014b).”
Electric field calculations in brain stimulation based on finite elements: An optimized processing pipeline for the generation and usage of accurate individual head models (2013, methodology): “In a similar vein, individualized field calculations might contribute to a better understanding of the origin of the ‘‘anisotropy’’ of motor evoked potentials as observed when rotating the TMS coil [Thielscher et al., 2011].”
The non-transcranial TMS-evoked potential is an inherent source of ambiguity in TMS-EEG studies (2018, methodology): “, 2015) using a 295 realistic head model automatically generated from the individual T1-weighted and T2-weighted MR 296 images as described elsewhere (Thielscher et al., 2015; Thielscher et al., 2011).”
Combining non-invasive transcranial brain stimulation with neuroimaging and electrophysiology: Current approaches and future perspectives (2016, positive): “For TMS (with a focal figure-of-eight coil) the direct effects of stimulation are relatively local and confined to the vicinity of the target site (Opitz et al., 2011; Thielscher et al., 2011).”
Causal Evidence for a Role of Theta and Alpha Oscillations in the Control of Working Memory (2020, background): “These models can be further specified by finite element models that indicate that the greatest induced electric field is in the gyral crown perpendicular to the coil angle [53].”
A guide for concurrent TMS-fMRI to investigate functional brain networks (2022, background): “Transcranial magnetic stimulation (TMS) allows for direct causal manipulation of the cerebral cortex by inducing an electric field in a focal region of the brain near the scalp (Thielscher et al., 2011; Deng et al., 2013; Siebner et al., 2022).”
Targeting neural oscillations with transcranial alternating current stimulation (2021, background): “With consistent laminar profiles across the cerebral cortex, electric field models often treat pyramidal neurons oriented from deep to superficial layers as the primary target for stimulation (Thielscher et al., 2011).”
Inferring Causality from Noninvasive Brain Stimulation in Cognitive Neuroscience (2020, background): “It is thus unlikely to exclusively stimulate a coordinate deep in the sulcus, limiting focal stimulation to the gyral crowns (Siebner, 2020; Thielscher et al., 2011).”