Follicular shuttling of marginal zone B cells facilitates antigen transport
By Guy Cinamon, Marcus A. Zachariah, Olivia M Lam, F. Foss, J. Cyster. Nature Immunology, 2008
602 citations recorded by the source corpus.
Subfields: Immunology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/315c5b09a98f07dcb879ee6894a5090a8ee80b71
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In Immunology
In Molecular Biology
- Susan R. Schwab
- F. Batista
- Naomi E. Harwood
- J. Cyster
- A. Olivera
- R. Proia
- S. Eisenbarth
- Sarah Spiegel
Citations in the corpus
- Finding a way out: lymphocyte egress from lymphoid organs (2007, background): “S1P 3 is abundant in marginal zone B cells, and recent work indicates it also contributes to B cell positioning in the marginal zon”
- The follicular versus marginal zone B lymphocyte cell fate decision (2009, background): “Injected immune complexes rapidly bind to B cells in the marginal zone, and the high levels of CD21 on marginal zone B cells could facilitate the transport of immune complexes from the circulation to the splenic follicles, where they could be captured by follicular dendritic cells for presentation t”
- THE ALLIANCE OF SPHINGOSINE-1-PHOSPHATE AND ITS RECEPTORS IN IMMUNITY (2008, background): “Through this S1P-driven shuttling mechanism, specialized B cells can pick-up antigens from the blood that filters through the marginal zone, deliver them to follicular DCs and then return back to the marginal zon”
- The who, how and where of antigen presentation to B cells (2009, background): “The mechanism by which marginal-zone B cells transport antigen from the marginal zone to the follicles was revealed by a recent study involving the treatment of chimeric mice with the sphingosine 1-phosphate receptor 1 ( S1PR1 ) antagonist FTY720 (Ref”
- Structure-function of the immune system in the spleen (2019, background): “Naïve follicular B cells reside in WP follicles, but once activated, B cells rapidly cycle between the light and dark zone of the GC. CXCR5 drives B cells to the light zone, where they receive T cell help, whereas CXCR4 drives them into the dark zone, where they undergo rapid proliferation, class sw”