The who, how and where of antigen presentation to B cells

By F. Batista, Naomi E. Harwood. Nature reviews. Immunology, 2009

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Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer. (2012, background): “These may be sampled by lymph noderesident DCs as well as blood or lymphatic endothelial cells, which in turn can affect the immunological outcome (38, 211, 253).”
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism (2010, background): “B cells exposed to antigen initially migrate to the T cell border, where they receive signals from antigen-activated CD4 T cells that promote their further migration to either the bridging channels as plasmablasts or their reentry to the follicles for the formation of GC (Batista and Harwood, 2009).”
Cancer immunotherapy via dendritic cells (2012, neutral): “The mechanism by which DCs route antigens into a non-degrading recycling compartment that results in the presentation of unprocessed antigens to B cells is poorly characterize”
FOLLICULAR HELPER T CELLS: LINEAGE AND LOCATION (2009, background): “Naive B cells will also encounter antigen in draining LNs very early after initial antigen priming (Batista and Harwood, 2009).”