The transcriptional role of PML and the nuclear body

By S. Zhong, P. Salomoni, P. Pandolfi. Nature Cell Biology, 2000

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How researchers see this paper

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Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies (2007, background): “In the absence of a clear understanding of the biochemical function of PML and its related structures, a few models have been proposed to explain how PML-NBs exert their biological function”
The role of PML in tumor suppression. (2002, neutral): “As a highly abundant pRb protein and the relevance of these consequence, the number and size of PML-NBs per interactions has only been proved for a few of them, nucleus increases ( Zhong et al., 2000b; Jensen et al., prompting a functional assessment of the PML/pRb in- 2001).”
Stem cell origin of cancer and differentiation therapy. (2004, background): “PML is normally found in a discrete, circumscribed nuclear structure called a nuclear body in cells of the myeloid series [268,269].”
The promise of retinoids to fight against cancer (2001, background): “We can only speculate about the possible functions of nuclear bodies in transcription regulatio”
Alternative lengthening of telomeres in mammalian cells (2002, background): “PNBs are the subject of many recent articles that are too numerous to cite here; the reader is referred to some of the many recent reviews (e.g., Hodges et al., 1998; Maul et al., 2000; Ruggero et al., 2000; Zhong et al., 2000).”