The genome sequence of Drosophila melanogaster.

By M. Adams, S. Celniker, R. Holt, C. Evans, J. Gocayne, P. Amanatides, S. Scherer, P. Li, R. Hoskins, R. Galle and 185 more. Science, 2000

6,282 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/30f1a8ebbac1f4decccc1b0de33dc37f39ebeb18

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Citations in the corpus

Two Rounds of Whole Genome Duplication in the Ancestral Vertebrate (2005, background): “For each cluster that contained only a single gene from each of the four chordate species, the highest scoring BLASTP match to the Drosophila melanogaster gene set [15] was added.”
A Protein Complex Network of Drosophila melanogaster (2011, background): “Moreover, despite the success of the extensive molecular genetic studies in Drosophila, one-third ( 14,000) of predicted Drosophila proteins (Adams et al., 2000) remains without functional annotation (Tweedie et al., 2009).”
Protease degradomics: A new challenge for proteomics (2002, background): “Surprisingly, Drosophila melanogaster , which has a gene content that is considerably lower than these vertebrate organisms, shows a similar number of protease genes as a result of the impressive expansion of a group of trypsin-like serine proteases in the fly genom”
A Research Agenda For DSM-V (2002, background): “Comparative sequencing of the fruit fly (Adams et al. 2000) and nematode worm has already defined a list of more than 2,000 genes that are orthologs of human genes, potentially enabling these other species to be used as models for the functions of the orthologous genes.”
Regulation of cellular growth by the Drosophila target of rapamycin dTOR. (2000, methodology): “…response to DNA damage (Hari et al. 1995); CG6535, a second ATMrelated gene of unknown function (Adams et al. 2000); CG4549, whose closest relative encodes the nonsensemediated mRNA decay protein SMG-1 in C. elegans (O’Connor and Anderson 1999; Adams et al. 2000); and the dTOR gene described here.”
Benchmarking transposable element annotation methods for creation of a streamlined, comprehensive pipeline (2019, background): “, human [2], Drosophila melanogaster 85 [20], Arabidopsis thaliana [21], rice [22,23], maize [4], etc.”
The COG database: new developments in phylogenetic classification of proteins from complete genomes (2001, methodology): “To this end, 19 895 protein sequences from the (nearly) complete genome of the nematode Caenorhabditis elegans (6) and 14 100 sequences from the genome of the fruit fly Drosophila melanogaster (7) were analyzed using the COGNITOR program, which assigns proteins to COGs on the basis of multiple genom”
Identification of the gene altered in Berardinelli–Seip congenital lipodystrophy on chromosome 11q13 (2001, background): “It has 87% identity to the mouse Gng3lg product and partial homology to the Drosophila CG9904 protei”