Non-equilibration of hydrostatic pressure in blebbing cells

By G. Charras, J. Yarrow, M. Horton, L. Mahadevan, T. Mitchison. Nature, 2005

651 citations recorded by the source corpus.

Subfields: Cell Biology, Ecology, Evolution, Behavior and Systematics

View Paper: https://www.semanticscholar.org/paper/30e7be6d08bf4e5fdc86d9752746e5b5500b506d

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In Cell Biology

In Ecology, Evolution, Behavior and Systematics

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Citations in the corpus

Aquaporin water channels in the nervous system (2013, neutral): “The observation that regional hydrostatic pressure changes within cells do not equilibrate in the cytoplasm on scales of 10 microns and 10 seconds 99 supports the possibility of pressure-induced formation of localized cell membrane protrusions.”
Microvesicles: mediators of extracellular communication during cancer progression (2010, background): “(Charras et al., 2005; Paluch et al., 2005; MuralidharanChari et al., 2009a) Myosin Pinching of vesicle neck during release of microvesicles (McConnell et al., 2009; Muralidharan-Chari et al., 2009a) Jo ur na l o f C el l S ci en ce Microvesicles and tumor-triggered blood coagulation A range of…”
A bottom-up approach to cell mechanics (2006, background): “This would, moreover, serve the recently revived interest in the biological relevance of the longitudinal (osmotic compression) modes as opposed to the transverse (or shear) modes of the cytoplas”
Actin dynamics, architecture, and mechanics in cell motility. (2014, background): “Blebs are membrane bulges that are dynamically extruded at the cell surface (54, 57).”
Blebs lead the way: how to migrate without lamellipodia (2008, background): “Indeed, if cytoplasmic components (ribosomes, mitochondria, vesicles and the cytoskeleton) are tightly packed (resulting in an effective cytoplasmic mesh size of ∼30nm), pressure equilibration over the whole cell is slower than the timescale of bleb growth, and active myosin motors need to be locali”
Riding the DUBway: regulation of protein trafficking by deubiquitylating enzymes (2006, positive): “Under hypoxic conditions, mitochondrially derived oxidants cause activation of AMPK; the compound metformin, which is commonly used to treat diabetes, activates AMPK, again, through mitochondrial oxidant production (Zou et al., 2004; Quintero et al., 2006).”
Mechanical Principles Governing Pollen Tube Growth (2007, background): “They cite Charras et al. (2005) and Langridge and Kay (2006) who observed that over short periods of time local cellular regions can undergo pressure changes that are only gradually equilibrated over the entire cell.”
Cell motility through plasma membrane blebbing (2008, methodology): “…JCB 879 JCB: MINI-REVIEW Correspondence to Oliver T. Fackler: oliver.fackler@med.uni-heidelberg.de; or Robert Grosse: robert.grosse@pharma.uni-heidelberg.de Abbreviations used in this paper: GPCR, G protein – coupled receptor; PM, plasma membrane; ROCK, Rho-associated kinase.”