Identification of a Testicular Odorant Receptor Mediating Human Sperm Chemotaxis
By M. Spehr, G. Gisselmann, A. Popławski, J. Riffell, C. Wetzel, R. Zimmer, H. Hatt. Science, 2003
760 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Sensory Systems
View Paper: https://www.semanticscholar.org/paper/2f9d871414c2a0d4b255fb4f133086eefa4f8998
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In Cellular and Molecular Neuroscience
In Endocrine and Autonomic Systems
In Sensory Systems
Citations in the corpus
- Patterns, mechanisms, and functions of translation regulation in mammalian spermatogenic cells (2004, background): “Fertilization of the egg is the ultimate measure of male reproductive success, and spermatozoa have evolved a variety of strategies to promote fertilization: high sperm motility (Birkhead, 2000), large numbers of sperm (Birkhead, 2000), chemotactic location of eggs (Spehr et al., 2003), resistance t”
- Olfaction: diverse species, conserved principles. (2005, neutral): “Good evidence exists that at least one human OR, hOR17-4, functions in the testis as well as the nose, responds to the chemical bourgeonal, and allows sperm to undergo chemotaxis toward bourgeonal sources (Spehr et al., 2003).”
- Genes and ligands for odorant, vomeronasal and taste receptors (2004, methodology): “The same group used the HEK293 system to show responsiveness to bourgeonal with a chimaeric version of the human OR17-4 (Ref”
- The biology of infertility: research advances and clinical challenges (2008, background): “For example, because human sperm express odorant receptors that aid in chemotaxis toward an oocyte, the fallopian tube or bot”
- Biological Physics of the Developing Embryo (2005, neutral): “, 1993), and perhaps in mammals as well (Spehr et al., 2003), the gradient sets the direction of the sperm’s velocity vector, for which the sperm itself, using the mechanism described, supplies the vector’s magnitude.”
- Sperm transport in the female reproductive tract. (2006, background): “Odorant receptors unique to sperm have been localized to a spot on the base of the flagellum of human (Spehr et al., 2003), canine (Vanderhaeghen et al., 1993) and rat sperm (Walensky et al., 1995).”
- Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation (2013, background): “ORs also play important roles outside of the OE, serving as specialized chemosensors in a variety of tissues (2, 3).”