Neurogenesis in the adult is involved in the formation of trace memories

By T. Shors, G. Miesegaes, A. Beylin, Mingrui Zhao, Tracy Rydel, E. Gould. 2001

2,115 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Developmental Neuroscience

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Citations in the corpus

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “…came from the effect of antimitotic agent MAM to block hippocampal neurogenesis and disrupt trace eye-blink conditioning and trace fear conditioning, but not contextual fear conditioning and spatial memory, all of which are considered hippocampus-dependent forms of memory (Shors et al., 2001).”
Adolescent cortical development: a critical period of vulnerability for addiction. (2007, background): “The contribution of adult hippocampal neurogenesis to learning and memory (Shors et al., 2001), as well as mood and affective state (Malberg et al.”
Structural Plasticity and Hippocampal Function (2010, background): “Acute stress also alters dendritic spine density on CA1 pyramidal cells of adult rats, but the direction of the effect is dependent on the sex of the animal, increasing the number of dendritic spines in males but decreasing the number of dendritic spines in females (Shors et al. 2001a).”
Impaired Adult Neurogenesis Associated with Short-Term Memory Defects in NF-κB p50-Deficient Mice (2008, background): “Although the role of adult neurogenesis remains to be fully elucidated, several studies have correlated changes in hippocampal neurogenesis with altered performance of hippocampus-dependent learning tasks, thus suggesting that ongoing neurogenesis in adulthood could be involved in functions such as ”
Neurogenesis in the adult brain: new strategies for central nervous system diseases. (2004, background): “Moreover, some correlative evidence has been accumulated that suggests that neurogenesis in these areas compensates for dying neurons (43) and is necessary for the functional integrity of these structures (44).”
New neurons in the dentate gyrus are involved in the expression of enhanced long‐term memory following environmental enrichment (2005, methodology): “In naı̈ve rats, MAM injections resulted in a substantial but not complete loss of BrdU-labelled cells in the dentate gyrus (see also Shors et al., 2001).”
Temporal and Spatial Dynamics of Brain Structure Changes during Extensive Learning (2006, result): “, 1998; Kempermann and Gage, 1998; Gage, 2002), one could argue that the changes seen in the hippocampus in our study may in fact resemble the exciting neural changes seen in rodents (Gould et al., 1999; van Praag et al., 1999, 2002; Shors et al., 2001; Kempermann et al., 2004).”
Neurogenesis may relate to some but not all types of hippocampal‐dependent learning (2002, background): “Moreover , it was previously reported that a similar reduction in cell proliferation impairs trace conditioning of the eyeblink response (Shors et al., 2001).”
Extreme sensitivity of adult neurogenesis to low doses of X-irradiation. (2003, background): “Furthermore, reductions in the number of newly generated neurons using the toxin methylazoxymethanal acetate impair learning (25), and recently, investigators using a hippocampal slice model showed that radiation-induced reductions in dentate neurogenesis were associated with an inhibition of long-t”