Physiological Migration of Hematopoietic Stem and Progenitor Cells

By Douglas E. Wright, A. Wagers, Anjali Gulati, Frances L. Johnson, Irving L. Weissman. Science, 2001

983 citations recorded by the source corpus.

Subfields: Genetics, Hematology, Oncology

View Paper: https://www.semanticscholar.org/paper/2dac7871b2fb863b342b74e7a10f8087cdf0aa08

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Citations in the corpus

Growth Differentiation Factor 11 is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy (2013, neutral): “1+) partners (Wright et al., 2001).”
The In Vitro Migration Capacity of Human Bone Marrow Mesenchymal Stem Cells: Comparison of Chemokine and Growth Factor Chemotactic Activities (2007, background): “The migration capacity of MSCs clearly stands in contrast to that of HSCs whose migration is induced mainly by a single chemokine, SDF-1 [33], while hematopoietic GFs display little or no chemotactic activity [34].”
The spleen in local and systemic regulation of immunity (2013, background): “, 2009) and can induce suppressive FoxP3 Treg cells from the naive T cell population (Yamazaki et al., 2008).”
No place like home: anatomy and function of the stem cell niche (2008, background): “HSCs can leave this niche, enter the circulation and return to the niche, and their proximity to endothelial cells may facilitate mobilization from the bone marrow into the circulatio”
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium (2004, methodology): “To test this hypothesis, we used the classical parabiotic mouse model, in which surgically conjoined mice develop an anastomosed vasculature, leading to complete blood chimaerism within 7–10 days after surger”
Origins of tumor-associated macrophages and neutrophils (2012, result): “These observations are in line with previous evidence that a small fraction of HSCs and progenitor cells exit the bone marrow and traffic through different extramedullary tissues, including the spleen (25, 26), and that in response to inflammatory stimuli, these cells produce tissue-resident cell po”
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist (2005, background): “Movement of HSCs/ HPCs between marrow (their main site of production) and blood is a physiological process (4, 5); few HSCs/HPCs circulate in blood.”
Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. (2007, methodology): “On the basis of the yield of CFU-Cs in surveyed organs, we estimate the total number of HSPCs resident in extramedullary nonlymphoid tissue to be at least twice as large as the average number of HSPCs circulating in murine blood (Wright et al., 2001b).”
Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis (2002, neutral): “Consistent with this notion is a recent report that HSCs rapidly and constitutively migrate through the bloo”