Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues.

By Steffen Massberg, P. Schaerli, Irina Knezevic-Maramica, Maria Koellnberger, N. Tubo, E. Moseman, I. Huff, T. Junt, Amy J. Wagers, I. Mazo and 1 more. Cell, 2007

721 citations recorded by the source corpus.

Subfields: Hematology, Immunology

View Paper: https://www.semanticscholar.org/paper/225aeabe74b74fc729874e02f4810cc739a287fc

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Citations in the corpus

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. (2009, positive): “A recent report indicates that HSPCs can circulate through the lymphatic system as well (Massberg et al., 2007).”
Blood monocytes: development, heterogeneity, and relationship with dendritic cells. (2009, background): “The CD14 + CD16 − monocytes represent 80% to 90% of blood monocytes, express high levels of the chemokine receptor CCR2 and low levels of CX3CR1, and produce IL-10 rather than TNF and IL-1 in response to LPS in vitro (117, 118) (10, 109).”
Rhythmic modulation of the hematopoietic niche through neutrophil clearance (2013, positive): “, 2005) and into tissues, where they participate in regenerative or immune processes (Laird et al., 2008; Massberg et al., 2007).”
The spleen in local and systemic regulation of immunity (2013, background): “Circulating HSPCs, which resist cell death by upregulating the don’t-eat-me signal CD47 (Jaiswal et al., 2009), traffic through peripheral tissues and lymph (Massberg et al., 2007) and can re-engraft bonemarrow niches (Wright et al., 2001).”