A sham‐controlled, phase II trial of transcranial direct current stimulation for the treatment of central pain in traumatic spinal cord injury

By Felipe Fregni, P. Boggio, M. Lima, M. J. Ferreira, Tim A. Wagner, Sergio P. Rigonatti, A. W. Castro, D. R. Souza, M. Riberto, S. Freedman and 2 more. Pain, 2006

688 citations recorded by the source corpus.

Subfields: Anesthesiology and Pain Medicine, Neurology, Surgery

View Paper: https://www.semanticscholar.org/paper/2cacd2e10ca7f1f695d80ac1c21a70fe84707538

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Citations in the corpus

The electric field in the cortex during transcranial current stimulation (2013, background): “…studies investigating the putative role of tDCS in the treatment of a variety of psychiatric and neurological disorders such as depression (Nitsche et al., 2009; Palm et al., 2012), epilepsy (Nitsche and Paulus, 2009), recovery from stroke (Nair et al., 2011), as well as pain (Fregni et al., 2006).”
Partially non‐linear stimulation intensity‐dependent effects of direct current stimulation on motor cortex excitability in humans (2013, methodology): “…therefore administered 2 mA cathodal and anodal tDCS for 20 min to the primary motor cortex of healthy subjects, which is a frequently used stimulation protocol in cognitive and clinical studies (Iyer et al. 2005; Fregni et al. 2006b; Ferrucci et al. 2009; Brunoni et al. 2011; Ladeira et al. 2011).”
Gyri –precise head model of transcranial DC stimulation: Improved spatial focality using a ring electrode versus conventional rectangular pad (2009, positive): “tDCS modulates cortical function and has been applied to facilitate learning, alter behavioral performance, and improve impaired brain function.(5-13) A pivotal factor for tDCS efficacy and safety is the spatial extent of induced cortical electric field (EF)/current density.”
Shaping the effects of transcranial direct current stimulation of the human motor cortex. (2007, background): “…relevant because they modify perception as well as cognition in healthy subjects (Antal et al. 2001, 2004a,b,c; Matsunaga et al. 2004; Nitsche et al. 2003) and were shown to improve clinical symptoms in patients with neuropsychiatric diseases (Fregni et al. 2005b, 2006a,b,c; Hummel et al. 2005).”
Phantom limb pain: a case of maladaptive CNS plasticity? (2006, neutral): “Stimulation of cortical areas that are hyperactive by transcranial magnetic stimulation or direct current stimulation might also be viable option”
Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases (2014, neutral): “negative results after five sessions of stimulation (Fregni et al., 2006d) 173 are opposed to a positive impact of 10 daily (Valle et al., 2009), or week- 174 ly sessions on pain ratings (Riberto et al., 2011), and another study, in 175 which a single session of orbitofrontal tDCS was conducted for…”