The Role of Drosophila Mushroom Body Signaling in Olfactory Memory

By Sean E. McGuire, P. T. Le, R. Davis. 2001

476 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Genetics, Immunology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Yoshinori Aso
2. Gerald M. Rubin
3. S. Waddell
4. Hiromu Tanimoto
5. Ronald L. Davis
6. Glenn C. Turner
7. T. Préat
8. P. Plaçais

In Genetics

1. Yoshinori Aso
2. S. Waddell
3. Gerald M. Rubin
4. Hiromu Tanimoto
5. Ronald L. Davis
6. Glenn C. Turner
7. T. Préat
8. Andrew C. Lin

In Immunology

1. S. Waddell
2. Hiromu Tanimoto
3. Yoshinori Aso
4. Ronald L. Davis
5. M. Krashes
6. T. Préat
7. Gerald M. Rubin
8. Jacob A. Berry

Citations in the corpus

• Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila (2014, background): “The mushroom body (MB) is the main center of associative memory in insect brains (de Belle and Heisenberg, 1994, Heisenberg et al., 1985; Dubnau et al., 2001; McGuire et al., 2001).”
• Recognition (2003, neutral): “…body (MB)/Kenyon cells (KCs) in insects—where sparse combinatorial codes are translated into associative memories, patterns, and behavioral decisions (de Belle & Heisenberg, 1994; Dubnau et al., 2001; Heisenberg et al., 1985; McGuire et al., 2001; Davison & Ehlers, 2011; Miyamichi et al., 2011).”
• The neuronal architecture of the mushroom body provides a logic for associative learning (2014, background): “DOI: 10.7554/eLife.04577 2 of 47 Research article Dubnau et al., 2001; McGuire et al., 2001), an associative center in the protocerebrum (Figure 1 and Video 1).”
• Olfactory representations by Drosophila mushroom body neurons. (2008, background): “1985) and genetic blockade of Kenyon cell synaptic output show that mushroom bodies are essential for memory formation and retrieval in fruit flies (Dubnau et al. 2001; Krashes et al. 2007; McGuire et al. 2001; Schwaerzel et al. 2002).”
• The GABAergic anterior paired lateral neuron suppresses and is suppressed by olfactory learning (2008, background): “Other options, such as expressing the temperature-sensitive Shibire”
• A map of olfactory representation in the Drosophila mushroom body. (2007, unknown): “MBs participate in the formation and retrieval of memories of olfactory associated experience (de Belle and Heisenberg, 1994; Dubnau et al., 2001; McGuire et al., 2001), courtship conditioning (McBride et al.”
• Drosophila olfactory memory: single genes to complex neural circuits (2007, methodology): “Using this method, Kenyon cell output was initially found to be dispensable during memory acquisition and storage but required for the retrieval of aversive and appetitive odour memor”
• Short and Long-term memory in Drosophila require cAMP signaling in distinct neuron types (2009, background): “Finally, reversible disruptions of dynamin-dependent neurotransmission in MB support the conclusion that output from a/b and/or g neurons is required during memory retrieval but not during acquisition or storage [26, 45, 46] (although it is worth noting that blocking 201Y g neurons alone does not ap”
• A Drosophila model for alcohol reward (2011, background): “, and store the associations in the specific neurons that are activated by a particular odo”