Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain.
By R. Simerly. Annual Review of Neuroscience, 2002
738 citations recorded by the source corpus.
Subfields: Behavioral Neuroscience, Cellular and Molecular Neuroscience, Developmental Neuroscience
View Paper: https://www.semanticscholar.org/paper/2bba86d1f29ab3c7a4bbe013675d9d765de2d2bf
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Citations in the corpus
- Differential regulation of KiSS-1 mRNA expression by sex steroids in the brain of the male mouse. (2005, background): “The AVPV receives sensory inputs from the BnST and medial amygdala and sends projections to the preoptic area (23), all of which are recognized to be involved in sexual behavior in the male (39).”
- Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone (GnRH) neurons (2006, background): “Female rodents are thought to possess a sexually differentiated, estrogen-receptive neuronal population located in the AVPV that is responsible for generating the GnRH surge (32, 34).”
- Sexual differentiation of the vertebrate nervous system (2004, background): “Sexually dimorphic brain regions are not always larger in males; the anteroventral periventricular nucleus (AVPV), part of the hypothalamic system regulating ovulatory cycles, is larger in females than in males, in both mice and rat”
- Regulation of Kiss1 gene expression in the brain of the female mouse. (2005, background): “This argument seems tenable, considering that perinatal exposure to E2 has long been known to direct the formation of sexually dimorphic circuits within the brain, particularly within the AVPV, and at least part of this effect is thought to be mediated by ER (12).”
- The pros and cons of phytoestrogens (2010, positive): “This distribution can change over the lifespan and is sexually dimorphic, particularly in the brain, suggesting that the two ER subtypes regulate different aspects of reproduction, behavior and neuroendocrine function and likely have differential roles across the lifespan [224,258].”
- Reward Processing by the Opioid System in the Brain (2009, neutral): “The hypothalamus is critically involved in coordinating the behavioral sequences as well as autonomic and endocrine responses associated with reproductive behavior (248, 314, 342).”
- Prenatal glucocorticoids and long-term programming. (2004, background): “However, 11 b - HSD-2 knockout mice also have low birth weight, and preliminary data suggest that null mice show several CNS aspects of the prenatal glucocorticoid ‘program-ming’ phenotype.”
- Molecular, Spatial and Functional Single-Cell Profiling of the Hypothalamic Preoptic Region (2018, neutral): “Second, cells that express tyrosine hydroxylase (Th), a key enzyme involved in catecholamine synthesis, have been viewed as a single population involved in several social behaviors (6, 39).”
- Sexually dimorphic neurons in the ventromedial hypothalamus govern mating in both sexes and aggression in males (2013, positive): “…influence on vertebrate sex-typical behaviors by controlling sex differences in the brain (Cooke et al., 1998; Dewing et al., 2003; Gagnidze et al., 2010; Jazin and Cahill, 2010; McCarthy and Arnold, 2011; Morris et al., 2004; Simerly, 2002; De Vries, 1990; Xu et al., 2012; Yang et al., 2006).”
- Report Visualizing Sexual Dimorphism in the Brain (2004, neutral): “ARexpressing neurons are scattered throughout the preopamygdala , the hypothalamus, the cortex, and the brainstem (Dong et al., 2001; Simerly, 2002).”
- Sex Differences in the Brain: The Not So Inconvenient Truth (2012, background): “…with men, while anorexia bulimia is three times as prevalent and anorexia nervosa is a disturbing 13 times more frequent in women (De Vries and Simerly, 2002; Simerly, 2002; Morris et al., 2004; Baron-Cohen et al., 2005; Cahill, 2006; Forger, 2009; McCarthy et al., 2009; Abel et al., 2010;…”