Regulation of Kiss1 gene expression in the brain of the female mouse.

By Jeremy T. Smith, M. Cunningham, E. Rissman, D. Clifton, R. Steiner. Endocrinology, 2005

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Kisspeptin signaling in the brain. (2009, background): “Second, in the mouse, the expression of Kiss1 mRNA in the AVPV is dramatically induced by estradiol (104, 144).”
Kisspeptins and reproduction: physiological roles and regulatory mechanisms. (2012, background): “As a whole, these studies have conclusively demonstrated that a prominent population of Kiss1 neurons resides in the ARC, or the equivalent infundibular region in primates, as documented in the mouse, rat, hamster, guinea pig, shrew, sheep, horse, pig, monkey, and human, either in terms of expressio”
Advances in male contraception. (2008, positive): “inhibition of kisspeptin production in the arcuate nucleus of the hypothalamus (67, 68).”
Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone (GnRH) neurons (2006, background): “This likely to be due to the very high density of kisspeptin fibers in the ARN that made it difficult to discern individual cell bodies, and the observation that kisspeptin biosynthesis is robustly suppressed by gonadal steroids in the ARN of intact male and female mice (22, 26).”