The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm.
By R. Kelly, N. Brown, Margaret E. Buckingham. Developmental Cell, 2001
901 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/2a2172bab8e491ba927d88e50497274d1e43a407
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Citations in the corpus
- Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. (2003, background): “…been described as being expressed in embryonic regions that overlap with and/or are adjacent to isl1-expressing cells, including BMPs 2, 4, 6, and 7 and Fgfs 4, 8, and 10 (Crossley and Martin, 1995; Dudley and Robertson, 1997; Kelly et al., 2001; Lyons et al., 1995; Niswander and Martin, 1992).”
- FGF/FGFR signaling in health and disease (2020, background): “FGF10 is found in the second heart field during early heart development,(430) and also expressed in progenitors for the right ventricle and outflow tract.(453) Neonatal mouse hearts possess the regenerative ability, but gradually lose this ability after postnatal day 7.”
- Building the mammalian heart from two sources of myocardial cells (2005, background): “Studies in mice also led to the identification of an anterior heart field as a source of outflow-tract myocardiu”
- Cardiac chamber formation: development, genes, and evolution. (2003, background): “At the anterior pole, recruited cells may have been exposed to signals like fibroblast growth factors (FGFs) and bone morphogenetic proteins (BMPs) in a manner different from the myocardium of the tubular heart (150, 204, 321).”