Air pollution: mechanisms of neuroinflammation and CNS disease

By M. Block, L. Calderón-Garcidueñas. Trends in Neurosciences, 2009

1,460 citations recorded by the source corpus.

How researchers see this paper

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Health effects of particulate air pollution: A review of epidemiological evidence (2011, background): “In addition to neuronal damage, systemic inflammation caused by air pollution may contribute to deteriorating olfactory, respiratory and blood-brain barriers to enhance access to the CNS and further increase in neuropathology (Block and Calderon-Garciduenas, 2009).”
Metals, oxidative stress and neurodegenerative disorders (2010, neutral): “In fact, the vast majority of articles reporting on the pathology of AD and to a lesser extent also to Parkinson’s disease (PD), related the origin of these neurodegenerative disorders with direct evidence supporting increased oxidative stress of the brain [8–10].”
Traffic Related Air Pollution, Particulate Matter, and Autism (2013, positive): “Emerging evidence suggests that systemic inflammation may also result in damage to endothelial cells in the brain and may compromise the blood-brain barrier.(29) Systemic inflammatory mediators may cross the bloodbrain barrier, activating brain microglia, and peripheral monocytes may migrate into th”
The Adverse Effects of Air Pollution on the Nervous System (2012, background): “The first histopathological evidence for a link between air pollution and neuropathology came from studies that were carried out on animal populations that are naturally exposed to polluted urban environments in Mexico City [1].”