Evolution of proteins and proteomes: a phylogenetics approach
By Toni Gabaldón. 2005
40 citations recorded by the source corpus.
The study of evolutionary relationships among protein sequences was one of the first applications of bioinformatics. Since then, and accompanying the wealth of biological data produced by genome sequencing and other high-throughput techniques, the use of bioinformatics in general and phylogenetics in particular has been gaining ground in the study of protein and proteome evolution. Nowadays, the use of phylogenetics is instrumental not only to infer the evolutionary relationships among species and their genome sequences, but also to reconstruct ancestral states of proteins and proteomes and hence trace the paths followed by evolution. Here I survey recent progress in the elucidation of mechanisms of protein and proteome evolution in which phylogenetics has played a determinant role.
Subfields: Molecular Biology, Spectroscopy
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The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- Jaime Huerta-Cepas
- Toni Gabaldón
- Joaquín Dopazo
- Hernán Dopazo
- Peer Bork
- Steven Kelly
- David M. Emms
- C. von Mering
In Spectroscopy
Citations in the corpus
- The human phylome (2007, methodology): “very useful tool for the detection of specific evolutionary scenarios [9] and for the functional characterization of genes and biological systems [10,11].”