Structural identification of a bacterial quorum-sensing signal containing boron

By Xin Chen, Stephan Schauder, N. Potier, A. Dorsselaer, I. Pelczer, B. Bassler, F. Hughson. Nature, 2002

1,552 citations recorded by the source corpus.

Subfields: Environmental Engineering, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/27fb3a530a5db097f480ef4c3df07be8ffc14177

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Environmental Engineering

1. N. Boon
2. W. Verstraete
3. B. Bassler
4. B. Logan
5. Korneel Rabaey
6. J. Regan
7. Derek R. Lovley
8. Abhijit Mukherjee

In Genetics

1. B. Bassler
2. Wai‐Leung Ng
3. S. Rutherford
4. Christopher M. Waters
5. Yung-Hua Li
6. Xiaolin Tian
7. Klaus Winzer
8. T. Defoirdt

In Molecular Biology

1. B. Bassler
2. Wai‐Leung Ng
3. T. Defoirdt
4. S. Rutherford
5. Christopher M. Waters
6. Peter Bossier
7. M. Givskov
8. Klaus Winzer

Citations in the corpus

• MOLECULAR SIGNALS AND RECEPTORS: CONTROLLING RHIZOSPHERE INTERACTIONS BETWEEN PLANTS AND OTHER ORGANISMS (2003, background): “3C), a furanosyl borate ester (AI2), peptides, or g-butyrolactones as intercellular signal molecules to coordinate behaviors of individual cells in a local population (Fuqua et al. 2001, Whitehead et al. 2001, Chen et al. 2002).”
• Natural occurrence of boron-containing compounds in plants, algae and microorganisms (2002, background): “harveyi , suggested that it was unlikely to resemble any of these molecules [127,128].”
• Quorum sensing: cell-to-cell communication in bacteria. (2005, background): “The second V. harveyi signal is a furanosyl borate diester known as AI-2 (Figure 2d and Bassler et al. 1994a, Chen et al. 2002), production of which requires the LuxS enzyme (Surette et al. 1999, Xavier & Bassler 2003).”
• Disruption of bacterial quorum sensing: an unexplored strategy to fight infections in aquaculture (2004, background): “A third major quorum sensing system was recently unravelled in the luminescent bacterium Vibrio harveyi (Chen et al., 2002).”
• Bacterial quorum sensing: its role in virulence and possibilities for its control. (2012, background): “DPD spontaneously converts into AI-2 (Table 3) (Surette et al. 1999; Schauder et al. 2001; Chen et al. 2002).”
• Molecular communication in the rhizosphere (2009, background): “In this latter bacterial group, 3- hydroxypalmitic acid methyl ester (Flavier et al. 1997), 3,4-dihydroxy-2-heptylquinoline (Holden et al. 1999), and a furanosyl borate diester (Chen et al. 2002) can also act as QS signals.”
• Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. (2003, background): “Autoinducer 2 (AI-2), a signaling molecule common to many diverse bacteria, has recently been described (17).”
• The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. (2002, background): “…antipar- the furanosyl borate diester bound by the bacterial quoallel barrel that defines the calyx, or cup-shaped ligand rum sensor protein LuxP; Chen et al., 2002) or to make binding site, and accessory elements (Flower et al., dramatic leaps in understanding protein function 2000).”