Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections.

By M. Hentzer, M. Givskov. Journal of Clinical Investigation, 2003

739 citations recorded by the source corpus.

Subfields: Microbiology, Molecular Biology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/b69e1708d69320034cbdf1da15508a6513123869

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. T. Bjarnsholt
2. Niels Høiby
3. M. Givskov
4. Søren Molin
5. Jorge M. Vivanco
6. O. Ciofu
7. H. Bais
8. Yung-Hua Li

In Molecular Medicine

1. T. Bjarnsholt
2. H. Bais
3. Jorge M. Vivanco
4. R. Aminov

Citations in the corpus

• Application of Quorum Quenching to Inhibit Biofilm Formation (2009, neutral): “Quorum quenching via blocking of quorum sensing by degradation of AHL molecules has been proposed as a promising alternative in several fields including aqua-culture, agriculture, and medicine (Hentzer and Givskov, 2003; Molina et al., 2003; Defoirdt et al., 2004; Dong and Zhang, 2005).”
• Effect of Essential Oils on Pathogenic Bacteria (2013, background): “Researchers are increasingly investigating herbal products in the quest for new therapeutic and anti-pathogenic agents that might act as nontoxic inhibitors of QS, thus controlling infections without encouraging the appearance of resistant bacterial strains [122].”
• Antibiotic resistance of bacterial biofilms. (2010, background): “Since it has been shown, that bacteria used for experimental animal 297 biofilm infections actually communicate in vivo (88) and also in e.”
• Quorum Sensing and Bacterial Social Interactions in Biofilms (2012, background): “Furanones inhibit bacterial colonization and biofilm formation through interference with acyl-HSL quorum-sensing pathway in Gram-negative bacteria [75].”
• The role of root exudates in rhizosphere interactions with plants and other organisms. (2006, background): “This has created an urgent need for new strategies to control bacterial infections (74).”
• Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics (2014, neutral): “aeruginosa biofilms exposed to furanones (308, 309).”