Innate lymphoid cells: emerging insights in development, lineage relationships, and function.

By H. Spits, T. Cupedo. Annual Review of Immunology, 2012

710 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/25a523222761c1277eb19dd23f365d464a5b557b

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Citations in the corpus

The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells. (2012, neutral): “ILCs are related to natural killer (NK) cells; they share with NK cells a dependency on the transcriptional repressor Id2, but whereas NK cells depend on IL-15, ILCs require IL-7 for their development and survival (reviewed in Spits and Cupedo, 2012).”
A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis (2013, background): “…these cells respond to IL-25 and IL-33 by producing type 2 cytokines, and in mice ILC2s have been shown to induce goblet cell hyperplasia and eosinophilia , and contribute to protection against helminth infections (Moro et al., 2010; Neill et al., 2010; Price et al., 2010; Spits and Cupedo, 2012).”
Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types (2017, background): “In addition, a large cluster of CD45RA + CD56 + NK cells and three distinct innate lymphoid cell (ILC) clusters with a characteristic lineage − CD7 + CD161 + CD127 + marker expression pro ﬁ le 19,20 are visualized.”
A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells (2013, background): “Leukocyte infiltration and epithelial injury were scored as absent, mild (1), moderate (2) or severe (3).”
Interleukin-22: immunobiology and pathology (2015, background): “ILCs can be defined by their differential expression of transcription factors (including Tbet, GATA3 or RORγt) and cytokines (such as IFNγ, IL-13, or IL-22) (64), largely mirroring CD4 helper T cell subsets.”
Innate lymphoid cells and asthma. (2014, neutral): “The initial reports of ILC2s described cell types with slightly different cell-surface markers and function,(24,27-29) but a consensus nomenclature panel renamed all of these type 2 ILCs because these cells secreted IL-5 and IL-13.(7) Although there are subtle differences between the cells described”