A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis
By M. Salimi, J. Barlow, Sean P Saunders, Luzheng Xue, D. Gutowska-Owsiak, Xinwen Wang, Li-Chieh Huang, David Johnson, S. Scanlon, Andrew N. J. McKenzie and 2 more. Journal of Experimental Medicine, 2013
927 citations recorded by the source corpus.
Type 2 innate lymphoid cells promote skin inflammation in mice and men, in part by producing IL-5 and IL-13 in response to IL-33
Subfields: Immunology, Surgery
View Paper: https://www.semanticscholar.org/paper/1347bdf4e3a135b4d1c6fa98da0cee2b705569e2
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Immunology
In Surgery
Citations in the corpus
- Innate Lymphoid Cells: a new paradigm in immunology (2015, background): “ILC2s and IL-13 are also associated with hepatic fibrosis induced in mice by thioacetamide, carbontetrachloride, and Schistosoma mansoni (109), and with pulmonary fibrosis (108), chronic rhinosinusitis (110), and atopic dermatitis (111, 112), as well as allergen- (112, 113) and rhinovirusinduced ast”
- Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch (2017, neutral): “However, we and others have recently shown that innate immune cell populations, such as group 2 innate lymphoid cells (ILC2s) and basophils, are critical mediators of skin inflammation independent of the adaptive immune system and are essential sources of type 2 cytokines in vivo (Kim et al., 2013, ”
- MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion (2014, background): “Human ILC2s Express MHCII and Present Antigen to T Cells In parallel studies, we assessed MHCII expression on purified human lineage–IL-7Ra+CRTH2+ ILC2s (Mjösberg et al., 2011; Salimi et al., 2013) (Figure S6D).”