Mesenchymal stem cells reside in virtually all post-natal organs and tissues

By L. Meirelles, P. Chagastelles, Nance B. Nardi. Journal of Cell Science, 2006

2,481 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics, Surgery

View Paper: https://www.semanticscholar.org/paper/2458664a25a94c9c24ce463fe7b04842cf85e4b8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. A. Caplan
2. T. Suda

In Genetics

1. A. Caplan
2. T. Suda
3. L. Meirelles
4. D. Prockop
5. Christopher S. Chen
6. Brendon M. Baker

In Surgery

1. A. Caplan
2. S. Goodman

Citations in the corpus

• Fate decision of mesenchymal stem cells: adipocytes or osteoblasts? (2016, background): “obtained from many tissues, such as bone marrow, umbilical cord, placenta, fat, lung, liver, and skin.(19,20) The most”
• Mesenchymal stem cell homing: the devil is in the details. (2009, neutral): “In addition to the passage number, confluency of the passaged cells, site of isolation, and properties of the media and incubation environment, it is critical to consider the heterogeneity in MSC surface receptor expression and resulting MSC behavior that has been observed both within and between st”
• Mechanisms involved in the therapeutic properties of mesenchymal stem cells. (2009, background): “When murine MSCs were plated at a single cell per well, the frequency of colony-forming clones was found to be nearly 50%, and when some of these clones were expanded and analyzed, they showed phenotypic characteristics similar to those of the parental populations [18].”
• Coordinated Changes of Mitochondrial Biogenesis and Antioxidant Enzymes During Osteogenic Differentiation of Human Mesenchymal Stem Cells (2008, background): “Adult human mesenchymal stem cells (hMSCs) are somatic stem cells residing in a variety of tissues [1], and they can differentiate into progenies of multiple lineages including osteoblasts, chondrocytes, adipocytes and hepatocytes.”
• Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow (2009, background): “…contrast, MSCs, which can give rise to multiple mesenchymal cell lineages, including adipocytes, chondrocytes, and osteocytes (Prockop, 1997; Pittenger et al., 1999), are currently isolated by culturing tissues from humans and other species (da Silva Meirelles et al., 2006; Beltrami et al., 2007).”
• Inflammation, Fracture and Bone Repair (2016, background): “sues including brain, pancreas, muscle, spleen, and lung [71].”
• The secretion profile of mesenchymal stem cells and potential applications in treating human diseases (2022, background): “MSC ISOLATION AND CHARACTERIZATION Well-characterized MSCs can now be isolated and propagated in vitro from multiple organs (such as BM, dental pulp, thymus, muscle, pancreas, and lung).(12) According to the International Society for Cellular Therapy (ISCT)-published minimal guidelines to define hum”
• Geometric cues for directing the differentiation of mesenchymal stem cells (2010, background): “M stem cells (MSCs) are multipotent cells that were initially isolated from bone marrow and noted for their ability to differentiate into bone cells (osteoblasts), cartilage cells (chondrocytes), and fat cells (adipocytes) (1, 2).”