Mechanism of auxin perception by the TIR1 ubiquitin ligase

By Xu Tan, L. I. Calderon-Villalobos, M. Sharon, Changxue Zheng, Carol V. Robinson, M. Estelle, N. Zheng. Nature, 2007

1,643 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/24494b4d26680a74f2f8a708f4277378d0db387e

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Citations in the corpus

Abiotic stress response in plants : when post-transcriptional and post-translational regulations control transcription (2008, background): “Sensing of auxin is accounted directly by the F-box protein of an E3 ligase, TYR1 [99], while gibberellins bind to a protein that, in turn, associates with an E3 ligase [100].”
Brassinosteroid signal transduction from receptor kinases to transcription factors. (2010, background): “It is yet unclear whether BRs function as a molecular glue, in a manner similar to auxin-induced TIR1-IAA protein dimerization (82), to help stabilize the BRI1 homo-dimer, or whether BR binding causes a conformational change that favors homo-dimerization.”
COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine (2008, background): “substrate recruitment by creating a surface on the leucine-rich repeat domain of TIR1 that facilitates Aux–IAA binding (20).”
Approaches and challenges to engineering seed phytate and total phosphorus (2009, neutral): “Phytic acid itself is incorporated in the core of a protein that functions in auxin signaling, the auxin receptor Transport Inhibitor Response 1 (TIR1) protein [112].”
Auxin receptors and plant development: a new signaling paradigm. (2008, background): “D (Dharmasiri et al. 2005a, Kepinski & Leyser 2005, Tan et al. 2007).”
Auxin Synthesized by the YUCCA Flavin Monooxygenases Is Essential for Embryogenesis and Leaf Formation in Arabidopsis[W] (2007, background): “In the presence of auxin, BDL is brought to the SCFTIR1-containing protein degradation machinery mediated by auxin binding directly to the auxin receptor TIR1 (Dharmasiri et al., 2005a; Kepinski and Leyser, 2005; Tan et al., 2007).”
Signaling network in sensing phosphate availability in plants. (2011, background): “It is worth noting that IP6 may function as a cofactor of the TIR1 auxin receptor, as revealed from the analysis of crystal structures (125).”
Molecular Basis of the Core Regulatory Network in ABA Responses: Sensing, Signaling and Transport (2010, background): “Mechanistic basis of hormone-induced signal transduction Structural studies of phytohormone receptors, auxin receptor TIR1 ( Tan et al. 2007 ) and gibberellin receptor GID1 ( Murase et al. 2008 , Shimada et al. 2008 ), have led to the proposition of two different modes for the hormone-induced…”