Effects of Vitamin D and Calcium Supplementation on Falls: A Randomized Controlled Trial

By H. Bischoff, H. B. Stähelin, W. Dick, Regula Akos, Margrith E Knecht, Christian Salis, M. Nebiker, R. Theiler, M. Pfeifer, B. Begerow and 2 more. Journal of Bone and Mineral Research, 2003

1,018 citations recorded by the source corpus.

Subfields: Orthopedics and Sports Medicine, Pathology and Forensic Medicine, Physiology

View Paper: https://www.semanticscholar.org/paper/23b4b55d48bacef83b56b7f981188e9f55448e85

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Citations in the corpus

Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. (2011, background): “subjects using 800 IU/d of vitamin D3 over 2 to 3 months (117, 121), the corrected pooled OR was 0.”
Vitamin D—Effects on Skeletal and Extraskeletal Health and the Need for Supplementation (2013, neutral): “Muscle strength [123] and postural and dynamic”
Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy. (2005, background): “A 3-month clinical trial of 122 patients in long-term care facilities demonstrated that daily vitamin D3 and calcium provided a 49% reduction in fall rates, compared with calcium alone (38).”
The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. (2012, background): “Asystematicreviewandmeta-analysiswascommissioned by The Endocrine Society to support the development of the Society’s guidelines on vitamin D (123).”
Effect of Vitamin D on falls: a meta-analysis. (2004, methodology): “The latter trial expected a moderately high dropout rate (powered for 30% drop-out) because all participants were on waiting lists for nursing home placement at study entry.(12) FIGURE 2 shows the forest plot of the primary analysis.”
Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. (2006, background): “A physiologic explanation for the beneficial effect of vitamin D on muscle strength is that 1,25-dihydroxyvitamin D (1,25(OH)2D), the active vitamin D metabolite, binds to a vitamin D–specific nuclear receptor in muscle tissue (65–67), which leads to de novo protein synthesis (54, 58), muscle cell g”
The effects of vitamin D on skeletal muscle strength, muscle mass, and muscle power: a systematic review and meta-analysis of randomized controlled trials. (2014, neutral): “Bischoff 2003 (21) 62 (100) Geriatric care 85.”
Estimates of optimal vitamin D status (2005, background): “Supplementation that increased mean serum 25(OH)D levels from 30 to 65 nmol/l lowered the total number of falls occurring in very elderly institutionalized women [22].”
Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or =60 y. (2004, background): “Randomized controlled trials (RCTs) found that nonvertebral fractures decreased by 58% in ambulatory elderly in the United States (1) and by 32% in institutionalized elderly in France (2).”
Vitamin D deficiency in adults: when to test and how to treat. (2010, background): “Vitamin D supplementation can improve muscle strength and reduce fall frequency by approximately 50%.(7) Thus, patients who have low bone mineral density or a prior low-impact (fragility) skeletal fracture and those at risk of falling should be evaluated for vitamin D deficiency to reduce the risk o”