D1/D5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus.

By Yan-You Huang, E. Kandel. 1995

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Translational regulatory mechanisms in persistent forms of synaptic plasticity. (2004, background): “D1/D5 agonists (Frey et (Linden, 1996). al., 1993; Huang et al., 1994; Huang and Kandel, 1995;”
Generalization of value in reinforcement learning by humans (2012, background): “Conversely, value information in the hippocampus may arrive via significant projections from midbrain dopaminergic neurons of the ventral tegmental area (Dahlström & Fuxe, 1964; Swanson, 1982; Frey et al., 1990; Gasbarri et al., 1994; Huang & Kandel, 1995; Otmakhova & Lisman, 1996).”
Gain in sensitivity and loss in temporal contrast of STDP by dopaminergic modulation at hippocampal synapses (2009, background): “In previous experiments, it was found that high concentration (250 M) of dopamine induced a late-phase potentiation in the CA1 area of hippocampus 1 h after application (27).”
ReviewThe Hippocampal-VTA Loop : Controlling the Entry of Information into Long-Term Memory (2005, unknown): “of dopamine on plasticity, i.e., inhibition of depotentia- 1990; Huang and Kandel, 1995).”
Neural mechanisms of addiction: the role of reward-related learning and memory. (2006, background): “Dopamine has been reported to modulate synaptic plasticity in several other brain regions including the amygdala (Bissiere et al. 2003) and hippocampus (Huang & Kandel 1995, Otmakhova & Lisman 1996).”
Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. (2003, background): “This signaling pathway may be involved in LTP at CA1 synapses, and is thought to include dopamine D1/D5 receptors, protein kinase A (PKA), and the cAMP-response-element-binding protein (CREB; Frey et al., 1993; Bourtchuladze et al., 1994; Huang and Kandel, 1995; Abel et al., 1997; Barad et al., 1998”
Dopamine: a potential substrate for synaptic plasticity and memory mechanisms. (2003, background): “This was later confirmed by Huang and Kandel (1995)who also showed that agonists of the D1/D5 receptors (SKF 38393) produced a persistent increase of the excitatory post-synaptic potential (EPSP) slope, with a very slow onset synaptic potentiation starting 50–90 min after drug application and…”
Dopamine Receptor Signaling (2004, background): “D1-like receptors increase NMDA receptor-mediated responses in neostriatal (83–86), hippocampal (87), and cortical neurons (88–91) and enhance phosphorylation of the NMDA-NR1 subunit.”
Reward-related fMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation (2005, background): “Dopaminergic neuromodulation is required for the maintenance of LTP (i.e., “late LTP”) in hippocampal CA1 (Frey et al., 1990, 1991; Huang and Kandel, 1995).”
Dopaminergic Modulation of Cortical Inputs during Maturation of Adult-born Dentate Granule Cells (2011, background): “A wealth of studies has been conducted on the regulatory role of DA in synaptic transmission and plasticity of CA1 pyramidal neurons (Huang and Kandel, 1995; Otmakhova and Lisman, 1996, 1999; Matthies et al., 1997; Lemon and Manahan-Vaughan, 2006); however, the functional significance of the DA…”