Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin.
By A. Asakawa, A. Inui, Oshihiro Kaga, H. Yuzuriha, T. Nagata, N. Ueno, S. Makino, M. Fujimiya, A. Niijima, M. Fujino and 1 more. Gastroenterology, 2001
1,236 citations recorded by the source corpus.
Subfields: Endocrine and Autonomic Systems, Endocrinology, Diabetes and Metabolism, Nutrition and Dietetics
View Paper: https://www.semanticscholar.org/paper/22225f1612699aec959b9e21a45654afcd819ea9
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In Endocrine and Autonomic Systems
In Nutrition and Dietetics
Citations in the corpus
- Ghrelin: structure and function. (2005, background): “Accordingly, the amino acid sequence of ghrelin has homology with that of motilin, another gastric peptide with gastric contractile activity (14, 65).”
- Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. (2004, background): “but also by afferent activity of the vagal nerve (137, 370).”
- Ghrelin causes hyperphagia and obesity in rats. (2001, background): “In addition recent reports have demonstrated inhibition of ghrelin-induced feeding by NPY Y1-receptor antagonists (25;26) and have shown upregulation of NPY (25;26) and AgRP (27) mRNA in the Arc following ghrelin administration.”
- A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. (2001, background): “Third, ghrelin affects feeding rapidly, increasing both food intake (6) and gastric acid secretion (7) within 20 min of intraperitoneal injection, a time course that is consistent with a role in meal initiation.”
- Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells. (2004, background): “Peripherally administered ghrelin has been shown to block IL-1β–induced anorexia (29) and produces positive energy balance by promoting food intake and decreasing energy expenditure.”
- Expression of ghrelin receptor mRNA in the rat and the mouse brain (2006, background): “…role in body weight homeostasis and have established ghrelin as an important indicator of energy insufficiency (Kamegai et al., 2000; Tschop et al., 2000; Asakawa et al., 2001, 2003; Cummings et al., 2001, 2002; Nakazato et al., 2001; Wisse et al., 2001; Wang et al., 2002; Yasuda et al., 2003).”