Nanosizing: a formulation approach for poorly-water-soluble compounds.

By E. Merisko-Liversidge, G. Liversidge, E. R. Cooper. European Journal of Pharmaceutical Sciences, 2003

1,301 citations recorded by the source corpus.

Subfields: Biomaterials, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/219005ece7fd846e1356a286c57ab605764df9e7

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Citations in the corpus

High drug-loading nanomedicines: progress, current status, and prospects (2017, neutral): “181 For intravenous administration, the smallness of this nanomedicine enables it to enter blood circulation and achieve targeted delivery through further surface modification.”
Nanotechnology: Intelligent Design to Treat Complex Disease (2006, background): “and its deposition at different places on the absorption sites especially when it is given orally (361,363,364).”
Strategies to Address Low Drug Solubility in Discovery and Development (2013, background): “The milling media must therefore be shown to withstand the milling process to avoid potential erosion and product contamination (Merisko-Liversidge et al., 2003).”
Nanosuspensions in drug delivery (2004, background): “A drive shaft, attached to rotating disks, provides the energy to a charge of crosslinked polystyrene beads to comminute the drug crystals by a compression–shear actio”
Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products. (2008, background): “…in general (Müller and Böhm, 1998; Müller et al., 1999a; Müller et al., 1999b; Müller et al., 2000a; Müller et al., 2000b; Müller et al., 2001; Merisko-Liversidge et al., 2003; Müller and Keck, 2004; Patravale et al., 2004; Rabinow, 2004; Rao et al., 2004; Gupta, 2006), their manufacturing…”
Nanotechnology applications in cancer. (2007, background): “solubility issues, which has significant implications because more than 40% of active substances being identified through combinatorial screening programs are poorly soluble in water (122).”
Antifungal activity and mode of action of silver nano-particles on Candida albicans (2009, neutral): “specific requirements in terms of size, shape, and physical and chemical properties is of great interest in the formulation of new pharmaceutical products ( Merisko-Liversidge et al. 2003; Brigger et al. 2002).”
Nanosuspension: An approach to enhance solubility of drugs (2011, background): “Paclitaxel nanosuspension was reported to have their superiority in reducing the median tumor burden.[43] Clofazimine nanosuspension showed an improvement in stability as well as efficacy above the liposomal clofazimine in Mycobacterium avium-infected female mice.”