Serine/threonine protein kinases and apoptosis.

By T. Cross, D. Scheel-Toellner, N. Henriquez, E. Deacon, M. Salmon, J. Lord. Experimental Cell Research, 2000

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PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? (2001, background): “…termed SB-415286 and SB-216763 (Coghlan et al., 2000), and these have also been shown, together with lithium, a less specific GSK3 inhibitor, to protect both central and peripheral nervous system neurons in culture from death induced by reduced PI 3-kinase pathway activity (Cross et al., 2000).”
New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway. (2004, background): “Jiang et al. [89] demonstrated cardio-protection in the isolated perfused rat heart when FGF was given during the first 12 min of reperfusion, following 30 min of global ischaemia, and protection was shown to be PKC-dependent.”