Innate immune sensing and its roots: the story of endotoxin

By B. Beutler, E. Rietschel. Nature reviews. Immunology, 2003

1,399 citations recorded by the source corpus.

Subfields: Immunology, Microbiology

View Paper: https://www.semanticscholar.org/paper/1fa776a4153bd2d2bdcddcf2eb0ddcd4dc75f412

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. B. B. Finlay
2. T. Roger
3. Thierry Calandra
4. Shizuo Akira
5. R. Medzhitov
6. Taro Kawai
7. O. Takeuchi
8. Satoshi Uematsu

In Microbiology

1. B. B. Finlay
2. Shizuo Akira

Citations in the corpus

• Gut microbiota in health and disease. (2010, background): “Systemic reactions to LPS lead to highly lethal septic shock (19), a very undesirable outcome of host-microbiota interactions.”
• Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. (2007, background): “LPS exerts multiple cellular effects by inducing signaling through TLR4 receptor (Beutler and Rietschel 2003; Palsson-McDermott and O’Neill 2004).”
• Macrophage migration inhibitory factor: a regulator of innate immunity (2003, background): “Endotoxins are a main virulence factor of Gram-negative bacteria 59 .”
• Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. (2006, background): “There is a huge body of literature concerning physiological responses to bacterial components (Beutler and Rietschel, 2003 and Taylor, 2001).”