Antibiotics as intermicrobial signaling agents instead of weapons

By J. Linares, I. Gustafsson, F. Baquero, J. Martínez. Proceedings of the National Academy of Sciences of the United States of America, 2006

680 citations recorded by the source corpus.

Subfields: Ecology, Molecular Biology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/1f73d172bdc4a16b7d9e4bc302a0368544bad24e

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Citations in the corpus

Horizontal transfer of antibiotic resistance genes in clinical environments. (2019, background): “Infectious disease 350 surveillance efforts must recognise plasmids as the possible unit of transmission as opposed to 351 classic clonal outbreaks of AR species (Conlan et al. 2014; Linares et al. 2006; Mathers et al. 352 2011; Tofteland et al. 2013).”
Call of the wild: antibiotic resistance genes in natural environments (2010, background): “Modulation of host transcription leads to metabolic and behavioural changes in the microorganisms, as has been described in several report”
Environmental factors influencing the development and spread of antibiotic resistance (2017, neutral): “Many antibiotics instead seem to primarily function as pigments, toxins, and effectors in microbial communities (Demain 1998), or be involved in microbial signaling (Linares et al. 2006).”
Antibiotics and antibiotic resistance in water environments. (2008, background): “(a kind of hormones) in microbial environments [44–46].”
The Rising Tide of Antimicrobial Resistance in Aquaculture: Sources, Sinks and Solutions (2017, background): “Of particular concern are the hormetic properties of antimicrobials, where higher concentrations of antimicrobials in close proximity of aquaculture sites may select for resistant bacteria, while sub-inhibitory concentrations of antimicrobial residues in surrounding water and sediments might stimula”
Antimicrobial use in aquaculture re-examined: its relevance to antimicrobial resistance and to animal and human health. (2013, background): “(Linares et al., 2006).”
Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer (2016, background): “Additionally, their function as cell-cell signaling molecules has been described (Davies, 2006; Linares et al., 2006).”
Probiotics and competitive exclusion of pathogens in shrimp aquaculture (2020, background): “Investigation into the functional role of sub-inhibitory concentrations of antimicrobials has revealed their multifaceted nature (Fajardo & Mart ınez, 2008), with involvements in signalling (Davies et al., 2006; Linares et al., 2007; Romero et al., 2011), inhibition of quorum sensing (Hong et al.”
Bacterial-Fungal Interactions: Hyphens between Agricultural, Clinical, Environmental, and Food Microbiologists (2011, background): “Interestingly, low concentrations of some antibiotics that do not induce bacterial stress responses can have signaling effects on bacterial biofilm formation and motility (105, 218).”