Call of the wild: antibiotic resistance genes in natural environments

By Heather K. Allen, Justin J. Donato, H. H. Wang, Karen A. Cloud-Hansen, J. Davies, Jo Handelsman. Nature Reviews Microbiology, 2010

2,159 citations recorded by the source corpus.

Subfields: Ecology, Molecular Medicine, Pollution

View Paper: https://www.semanticscholar.org/paper/6f6958497c266113e042f5a0deb5475b8bfd1f9c

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Citations in the corpus

Antibiotic resistance in the environment: a link to the clinic? (2010, background): “The role of these organisms as potential reservoirs of resistance genes is only now becoming a focus of research [6 ,7,8].”
Antibiotic resistance plasmids in wastewater treatment plants and their possible dissemination into the environment (2010, background): “It is well established that ARB and ARGs existed prior to widespread antibiotic use (Hall and Barlow, 2004; Martinez, 2009a,b; Allen et al., 2010), however, the importance of the non-clinical environment in the increase of antibiotic resistance to clinical pathogens remains unclear (Martinez, 2009a;”
Acquired Antibiotic Resistance Genes: An Overview (2011, background): “Over the last decades they have remained a reason for concern, but additional public health threats in relation to resistant microorganisms have also arisen (see for example Cantón et al., 2008; Goossens, 2009; Allen et al., 2010).”
Bacterial phylogeny structures soil resistomes across habitats (2014, background): “Unlikemosthospitalsettings,soilscontainahugediversityofARGs 1–3, 16, 22 ,”
Correlation of tetracycline and sulfonamide antibiotics with corresponding resistance genes and resistant bacteria in a conventional municipal wastewater treatment plant. (2012, background): “Hence, large amounts of antibiotics and their metabolites are potentially released into different compartments of the environment, which are regarded as the most important factor for the evolution and selection of antibiotic resistance in bacterial pathogens (Allen et al., 2010).”
Antimicrobial use in aquaculture re-examined: its relevance to antimicrobial resistance and to animal and human health. (2013, background): “…selected by residual antimicrobials in water and sediments (Kruse and Sørum, 1994; Davison, 1999; Alonso et al., 2001; Fricke et al., 2008; Cantón, 2009; Martinez, 2009a; 2012; Allen et al., 2010; Fondi and Fani, 2010; Colomer-Lluch et al., 2011; Stokes and Gillings, 2011; Dantas and Sommer, 2012).”
Environmental factors influencing the development and spread of antibiotic resistance (2017, neutral): “Given that most antibiotics in use are derived from natural compounds produced by microorganisms in the environment, the presence of genes conferring resistance to those compounds across a range of habitats is not surprising (Allen et al. 2010; Pal et al. 2016).”
Antibiotic Use in Agriculture and Its Consequential Resistance in Environmental Sources: Potential Public Health Implications (2018, background): “This is, however, possible due to the fact that the antibiotic resistance genes are located on elements, including transposons, integrons, and plasmids, that can be immobilized [99].”
Removal of antibiotic resistance genes (ARGs) in various wastewater treatment processes: An overview (2020, background): “…can promote the production of antibiotic resistant bacteria (ARBs) and antibiotic resistance genes (ARGs), subsequently leading to the prevalence of antimicrobial resistance (AR) (Allen et al., 2010; Bouki et al., 2013; Davies & Davies, 2010; Wang, Ma, et al., 2020), as shown in Figure 1.”