Dendritic cells in a mature age

By C. Reis e Sousa. Nature reviews. Immunology, 2006

1,058 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/1f0bd85d6795fc6662eaf1e28dd1377d76901824

How researchers see this paper

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In Immunology

1. K. Palucka
2. Jacques Banchereau
3. H. Hammad
4. B. Lambrecht
5. O. Joffre
6. M. Nolte
7. R. Spörri
8. C. Reis e Sousa

Citations in the corpus

• MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells (2009, background): “Each dot represents one miRNA probe [(1) hsa miR-155, (2) ambi miR-7084, (3) hsa miR-340, (4) hsa miR-368, (5) mmu miR-350].”
• Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma (2008, background): “One possible explanation is that, in naive mice, harmless antigens encountered by lung-derived DCs cannot fully activate the DCs to induce an effective T-cell respons”
• The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. (2013, background): “This process, called DC maturation, occurs in the steady state and upon inflammation (10, 50), but in contrast to steady-state migratory cDCs, those that migrate in response to inflammation also produce inflammatory cytokines and upregulate costimulatory molecules that drive adaptive immunity (for a”
• House dust mite allergen induces asthma via TLR4 triggering of airway structural cells (2009, background): “The phenotypic changes observed in pathogen-associated molecular pattern–activated DCs usually—but not always—correlate with an increased capacity of the cells to stimulate antigen-driven T cell proliferation and differentiatio”
• Cancer immunotherapy via dendritic cells (2012, positive): “Some of the CLRs, which are receptors for both PAMPs and endogenous ligands, have signalling motifs in their cytoplasmic regions that deliver either activation or suppression signal”
• Inflammatory signals in dendritic cell activation and the induction of adaptive immunity (2009, background): “As both directly and indirectly activated DCs have similar potential to interact with naive T cells (46), the consequence of this number disparity is that a self-reactive non-tolerant T cell would be more likely to encounter its cognate antigen on an indirectly activated DC than on a directly activa”
• Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes. (2010, methodology): “S3D) were used as a reference T-cell–stimulating population (27).”